Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3693

Full Length Research Paper

Insignificant activity of Allium paradoxium and Tanacetum parthenium on protoscoleces of Echinococcus granulosus: In vitro study

Elham Raeisi
  • Elham Raeisi
  • Department of Microbiology, Health center laboratory, Ardabil University of Medical Sciences, Ardabil, Iran.
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Bahman Rahimi Esboei
  • Bahman Rahimi Esboei
  • Department of Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Iran.
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  •  Received: 23 May 2016
  •  Accepted: 05 October 2016
  •  Published: 10 November 2016

Abstract

Medicinal plants are now recognized as most important alternative for chemical drugs resource, especially for anti-microbial targets. The current study aimed to determine the scolicidal effect of Allium paradoxium and Tanacetum parthenium as medicinal plants in vitro. Protoscoleces were exposed to different concentrations of chloroformic and hydroalcholic extracts (1, 10, 50 and 100 mg/mL) for 5, 10, 30, 60 and 120 min. Viability of protoscolices was confirmed by 0.1% Eosin staining. The results of this study showed that all extracts used were not significantly effective in comparison with the control group. Therefore, chloroformic and hydroalcholic extracts of A. paradoxium and T. parthenium could not be used during hydatid cyst treatment. However, there remains the need to perform advanced comparative clinical studies on the efficacy of A. paradoxium and T. parthenium and other scolicidal agents. Chloroformic and hydroalcoholic extract of A. paradoxium and T. parthenium, did not show any scolicidal activity at the concentration of 1, 10, 50 and 100 mg/ml.

Key words: Allium paradoxium, Tanacetum parthenium, Echinococcus granulosus, in vitro.