Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3843

Full Length Research Paper

In vitro anti-malarial activity of 20 quinones isolated from four plants used by traditional healers in the Democratic Republic of Congo

J. S. Kayembe*, K. M. Taba, K. Ntumba, M. T. C. Tshiongo and T. K. Kazadi
Department of Chemistry, Faculty of Sciences, University of Kinshasa, Democratic Republic of Congo, P. O. Box 190, Kinshasa XI.
Email: [email protected]

  •  Accepted: 28 January 2010
  •  Published: 04 June 2010

Abstract

The anti-malarial activity of 20 quinones isolated from Cassia alata, Cassia occidentalis, Garcinia kola and Ocimum basilicum was investigated in vitrousing the micro dilution test of Desjardin by a visual evaluation on thin blood smears. The six quinones isolated from C. occidentalis, three from C. alata and three from O. basilicum were found to be the most active with an IC50 value of below 1 µg/ml. The others quinones showed moderate activity with IC50 values of between 5 and 20 µg/ml.

 

Key words: Cassia alata, Cassia occidentalis, Garcinia kola, Ocimum basilicum, quinones, anti malarial activity, in vitro.

Copyright © 2025 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 4 No. 11
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES