Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3582

Review

A review on the botanical aspects, phytochemical contents and pharmacological activities of Warburgia ugandensis

Youngmin Kang
  • Youngmin Kang
  • Korean Medicine Life Science Major, University of Science and Technology (UST), Republic of Korea.
  • Google Scholar
Motlalepula Gilbert Matsabisa
  • Motlalepula Gilbert Matsabisa
  • Department of Pharmacology Faculty of Health Sciences University of Free State, Bloemfontein, 9300 South Africa.
  • Google Scholar
Denis Okello
  • Denis Okello
  • Korean Medicine Life Science, University of Science and Technology (UST), Republic of Korea.
  • Google Scholar
Richard Komakech
  • Richard Komakech
  • Korean Medicine Life Science, University of Science and Technology (UST), Republic of Korea.
  • Google Scholar


  •  Received: 14 June 2018
  •  Accepted: 09 August 2018
  •  Published: 10 November 2018

Abstract

Warburgia ugandensis Sprague (Family Canellacea) commonly known as Ugandan greenheart or pepper bark tree, is a highly valued medicinal plant in traditional medicine with a broad spectrum of antimicrobial activity whose parts especially the leaves and stem bark have for long been used in the treatment and management of many diseases and health conditions such as stomachache, cough, toothache, fever, malaria, oral thrush, measles and diarrhea in African communities where the plant occurs. This review focused on the phytochemical contents, medicinal uses and antimicrobial activities of W. ugandensis based on published peer reviewed articles. This review established that the high therapeutic value of W. ugandensis is attributed to the abundance of drimane sesquiterpenes in its stem bark and leaves. These chemicals have also made the plant to have potent antibacterial and antifungal activities. However, more pre-clinical and clinical trials need to be done to further validate the traditional medicine applications of W. ugandensis for possible drug discovery. Due to its high demand, W. ugandensis has been over exploited and hence its population is in drastic decline. Consequently, there is need for development of advanced and more rapid propagation techniques to increase its population and distribution in its natural environment to meet the ever-increasing demand.

Key words: Antimicrobial, Canellaceae, medicinal uses, phytochemicals, Warburgia ugandensis.