Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3584

Full Length Research Paper

Chemical composition, oviposition deterrent and larvicidal activities of the wood extracts of Tabebuia avellanedae from the Cerrado of Brazil

Jaqueline Cibene Moreira Borges
  • Jaqueline Cibene Moreira Borges
  • Department of Biotechnology, Biodiversity and Graduate School of Biotechnology of Amazonia (Bionorte) Gurupi, Federal Universiy of Tocantins, Brazil.
  • Google Scholar
Eder Alves Pereira e Silva
  • Eder Alves Pereira e Silva
  • Department of Biotechnology, Federal University of Tocantins, Gurupi, TO, Brazil.
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Tarcísio Castro Alves de Barros
  • Tarcísio Castro Alves de Barros
  • Department of Vegetable Production, Federal University of Tocantins (UFT)-Campus de Gurupi, Brazil.
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Ilsamar Mendes Soares
  • Ilsamar Mendes Soares
  • Department of Biotechnology, Biodiversity and Graduate School of Biotechnology of Amazonia (Bionorte) Gurupi, Federal Universiy of Tocantins, Brazil.
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Sergio Donizeti Ascencio
  • Sergio Donizeti Ascencio
  • Department of Biotechnology, Biodiversity and Graduate School of Biotechnology of Amazonia (Bionorte) Gurupi, Federal Universiy of Tocantins, Brazil.
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Rodrigo Ribeiro Fidelis
  • Rodrigo Ribeiro Fidelis
  • Department of Vegetable Production, Federal University of Tocantins (UFT)-Campus de Gurupi, Brazil.
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Raimundo Wagner de Souza Aguiar
  • Raimundo Wagner de Souza Aguiar
  • Department of Biotechnology, Biodiversity and Graduate School of Biotechnology of Amazonia (Bionorte) Gurupi, Federal Universiy of Tocantins, Brazil.
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  •  Received: 20 July 2018
  •  Accepted: 20 August 2018
  •  Published: 10 October 2018

Abstract

Tabebuia avellanedae is an important timber source belonging to the family of Bignoniaceae. The latter is known for its richness in terms of variety of bioactive chemical constituents, and it has been used in folk medicine for treatment of various diseases. The aim of this work was to investigate the chemical composition, oviposition deterrent and larvicidal activities of the wood extracts of T. avellanedae from the Cerrado of Brazil. Extracts of acetone, ethyl acetate and ethanol from T. avellanedae were obtained using various extraction methods. Quantitative analysis of phytochemical screening confirmed the presence of phenols and tannins in the wood extracts, however, anthraquinones, coumarins and alkaloids were absent. The toxicity of T. avellanedae extracts against 3rd instar larvae of Aedes aegypti using maceration and Soxhlet extraction methods was analyzed. The acetone and ethyl acetate extracts obtained by Soxhlet extraction were more toxic against 3rd instar A. aegypti larvae, with CL50of 100.1 and 151.0 μg/mL, respectively. The mortality values (LT50 and LT95) were 38.66 and 66.74 min for ethyl acetate extract, respectively, and 53.47 and 119.96 min for acetone extract, respectively. In all cases, the assay showed that all extracts presented mortality of 100% to 3rd instar larvae after 12 h. The oviposition assay showed that gravid A. aegypti females laid their eggs preferentially in the control ovitraps. The ethanol extract at 333.3 μg/mL strongly deterred oviposition by 89.89% while the ethyl acetate and acetone extracts presented 89.04 and 68.10% deterrence, respectively. The bioactive compounds in T. avellanedae make it a potential source for the control of A. aegypti vectors, without promoting deforestation of trees.

Key words: Mosquitoes, larvae, toxicity, Ipê-roxo, Aedes aegypti, phytochemical, phenolic compounds.