Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3806

Full Length Research Paper

Isolation and structural elucidation of chemical constituents of Mussaenda hainanensis Merr.

Yu-xian Li1, Wen-tao Qiao1 and Ke Yuan2*
1College of Pharmacy, Henan University of Traditional Chinese Medicine, Zhengzhou 450008, P.R. China. 2The Nurturing Station for the State Key Laboratory of Subtropical Silviculture, Zhejiang Agriculture and Forestry University, Lin’an, 311300, China.
Email: [email protected]

  •  Accepted: 22 February 2011
  •  Published: 18 April 2011


To study the chemical constituents of Mussaenda hainanensis Merr. and also researched the EtOAc, n-BuOH and H2O extract of 70% EtOH extract on DPPH radicals scavenging effect. The compounds were isolated by Diaion HP-20, Sephadex LH-20, Toyopearl HW-40 and Si gel column chromatography methods. Their structures were identified by physicochemical properties and spectroscopic analysis. Twelve compounds were elucidated as pinostrobin(1), quercetin(2), 8-O-acetyl-shanzhiside methyl ester(3), 8[E]-N-[2’-hydroxyl-tetracosan- cosoyl]-1-O-β- D-glucopyranosy1-8-en-octadecas-phingenine(4),caffeic acid (5), quercetin-3-O-β-D-glucosid(6), quercetin-7-O-β-D- glucoside(7), 3β-O-β-D-gluco-pyranosyl pomolic acid 28-O-β-D-glucopyranosyl ester(8), 3,4-di-o-caffeoylquinic acid(9), chlorogenic acid(10), lamalbid(11), shanzhiside methyl ester(12). The compounds were isolated from the plant for the first time. All the parts of the 70% EtOH extract and compounds 1~3, 5~7, 9~12 have the ability to scavenge DPPH free radical. The results provide evidence for the further research of its efficacy and its further development and utilization.


Key words: Mussaenda hainanensis Merr., chemical constituents, DPPH, antioxidant activity.