Full Length Research Paper
To study the chemical constituents of Mussaenda hainanensis Merr. and also researched the EtOAc, n-BuOH and H2O extract of 70% EtOH extract on DPPH radicals scavenging effect. The compounds were isolated by Diaion HP-20, Sephadex LH-20, Toyopearl HW-40 and Si gel column chromatography methods. Their structures were identified by physicochemical properties and spectroscopic analysis. Twelve compounds were elucidated as pinostrobin(1), quercetin(2), 8-O-acetyl-shanzhiside methyl ester(3), 8[E]-N-[2’-hydroxyl-tetracosan- cosoyl]-1-O-β- D-glucopyranosy1-8-en-octadecas-phingenine(4),caffeic acid (5), quercetin-3-O-β-D-glucosid(6), quercetin-7-O-β-D- glucoside(7), 3β-O-β-D-gluco-pyranosyl pomolic acid 28-O-β-D-glucopyranosyl ester(8), 3,4-di-o-caffeoylquinic acid(9), chlorogenic acid(10), lamalbid(11), shanzhiside methyl ester(12). The compounds were isolated from the plant for the first time. All the parts of the 70% EtOH extract and compounds 1ï½ž3, 5~7, 9~12 have the ability to scavenge DPPH free radical. The results provide evidence for the further research of its efficacy and its further development and utilization.
Key words: Mussaenda hainanensis Merr., chemical constituents, DPPH, antioxidant activity.
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