Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3804

Full Length Research Paper

Phytochemical and antimicrobial studies on extractives of Calyptrochilum emarginatum (SW) Schltr (Orchidaceae) growing in Nigeria

S. E. Okhale
  • S. E. Okhale
  • Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P. M. B. 21 Garki, Abuja, Nigeria.
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G. E. Ugbabe
  • G. E. Ugbabe
  • Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P. M. B. 21 Garki, Abuja, Nigeria.
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O. Bamidele
  • O. Bamidele
  • Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P. M. B. 21 Garki, Abuja, Nigeria.
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G. A. Ajoku
  • G. A. Ajoku
  • Department of Microbiology and Biotechnology, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P. M. B. 21 Garki, Abuja, Nigeria.
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H. O. Egharevba
  • H. O. Egharevba
  • Department of Medicinal Plant Research and Traditional Medicine, National Institute for Pharmaceutical Research and Development, Idu Industrial Area, P. M. B. 21 Garki, Abuja, Nigeria.
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  •  Accepted: 12 January 2014
  •  Published: 25 January 2014

Abstract

Calyptrochilum emarginatum is an epiphytic shrub belonging to the orchid family with numerous medicinal uses. Phytochemical investigation of the leaf extractives revealed the presence of tannins, flavonoids, carbohydrates, terpenes, sterols and saponins. Alkaloids and cardiac glycosides could not be detected. Antimicrobial studies of the extracts revealed that at a minimum inhibitory concentration (MIC) of 1.6 mg/ml, the hexane and methanol successive extracts exhibited bactericidal activities against Staphylococcus aureus. The straight run methanol extract and the successive ethyl acetate extract did not show any activity against all the microorganisms investigated namely, S. aureus, Candida albicans, Klebsiella pneumonia, Escherichia coli and Salmonella paratyphi at the same concentration.

Key words: Calyptrochilum emarginatum, orchid, phytochemicals, antimicrobial, minimum inhibitory concentration (MIC).

Copyright © 2023 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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