Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3843

Full Length Research Paper

Phytochemical profile and antibacterial activity of bark and leaves of Caesalpinia pyramidalis Tul. and Sapium glandulosum (L.) Morong.

Carlos Henrique Tabosa Pereira da Silva1*, Tadeu José da Silva Peixoto Sobrinho1, Antônio Marcos Saraiva2, Maria Nelly Caetano Pisciottano2 and Elba Lúcia Cavalcanti de Amorim1
1Natural Products Laboratory, Pharmaceutical Science Department, Federal University of Pernambuco, Av. Arthur de Sá, s/n, 50740-521, Cidade Universitária - Recife-PE, Brazil. 2Microbiological Analysis Laboratory, Pharmaceutical Science Department, Federal University of Pernambuco, Recife-PE, Brazil.
Email: [email protected]

  •  Accepted: 07 June 2012
  •  Published: 31 August 2012

Abstract

This study aimed to analyze the phytochemical profile and antibacterial activity of crude ethanol extracts (CEE) from the bark and leaves of Caesalpinia pyramidalis Tul. andSapium glandulosum (L.) Morong. The phytochemical composition was analyzed by thin layer chromatography (TLC) using eluent and specific revealing. Antibacterial activity was evaluated using the agar diffusion method (well technique) and determining the minimum inhibitory concentration (MIC). The extracts showed anthocyanins, sterols, flavonoids, coumarins, lignans and terpenoids. The results showed that the CEE from the barks of C. pyramidalis showed antibacterial activity against Staphylococcus aureus, Staphylococcuscoagulase-negative and Enterococcus faecalis, while the CEE from the barks and leaves ofS. glandulosum was active against S. aureus and S. coagulase negative. The CEE from the bark C. pyramidalis had MICs of 125 to 500 µg/ml. The antimicrobial activity of the extract of bark of C. pyramidalis indicate that the mechanism of multidrug resistance ofStaphylococcus to current antibiotics does not confer resistance to the compounds present in samples, which provides motivation for the isolation of chemicals responsible for such activities.

 

Key words: Antibacterial, burra-leiteria, catingueira, multidrug resistance, Staphylococcus.

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