Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3843

Short Communication

Isolation and spectral characterization of a new biaurone from Pongamia pinnata (L.) Pierre. (Fabaceae) pods

Pramod Kumar1, Munesh Kumar2* and Rainer W. Bussman3
1Department of Pharmaceutical Sciences, H.N.B. Garhwal University, Srinagar-Garhwal, Uttarakhand, 246174, India. 2Department of Forestry, H.N.B. Garhwal University, Srinagar-Garhwal, Uttarakhand, 249161, India. 3William L. Brown Center, Missouri Botanical Garden, St. Louis, MO 63110, USA.
Email: [email protected]

  •  Accepted: 23 February 2012
  •  Published: 17 October 2012

Abstract

Pongamia pinnata (L.) Pierre. (Fabaceae) locally known as karanja is widely used to treat rheumatic pains, hypertension, bronchitis, whooping cough, and skin diseases. The present study attempts to isolate new compounds from a methanolic extract of P. pinnata pods. A novel light green, amorphous, powdered compound has been isolated from chloroform: methanol ratio (8.2:1.8) eluent through column chromatography, and is named pongamiabiaurone. The molecular weight of the new compound was determined as 716 by electron impact mass spectroscopy. Through a combination of 1HNMR and 13CNMR spectral analysis, the structure of pongamiabiaurone was confirmed as 3-tetradecanoxy-4’-methoxy auronyl (13→13)-3’hydroxy-4’-methoxyaurone.

 

Key words: Methanolic extract, Pongamia pinnata, streptozotocin, diabetes mellitus.

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