Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3672

Full Length Research Paper

Oxidative stabilization of palm olein with isoespintanol (2-isopropyl-3,6-dimethoxy-5-methylphenol) isolated from Oxandra cf xylopioides

Karol Zapata
  • Karol Zapata
  • Research Group Chemistry of Natural Products and Food, Universidad Nacional de Colombia, Medellin, Colombia
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Juan P. Arias
  • Juan P. Arias
  • Research Group Chemistry of Natural Products and Food, Universidad Nacional de Colombia, Medellin, Colombia
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Farid B. Cortés
  • Farid B. Cortés
  • Research Group Surface Phenomena-Michael Polanyi- Universidad Nacional de Colombia, Medellin, Colombia
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Camilo L. Alarcon
  • Camilo L. Alarcon
  • Department of Pharmacy, Faculty of Chemistry – Pontificia Universidad Católica de Chile, Santiago de Chile, Chile
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Diego L. Durango Restrepo
  • Diego L. Durango Restrepo
  • Research Group Chemistry of Natural Products and Food, Universidad Nacional de Colombia, Medellin, Colombia
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Benjamín A. Rojano
  • Benjamín A. Rojano
  • Research Group Chemistry of Natural Products and Food, Universidad Nacional de Colombia, Medellin, Colombia
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  •  Received: 05 October 2016
  •  Accepted: 03 March 2017
  •  Published: 17 March 2017

Abstract

Antioxidants are used to retard oxidative processes and improve the sensory and nutraceutical quality of cooking oils. Isoespintanol, a monophenol isolated from Oxandra cf. xylopioides, has shown a greater free radical scavenger ability than thymol (biosynthetic analog).  Isoespintanol antioxidant capacity was evaluated and compared to butylated hydroxytoluene (BHT). Cytotoxicity, thermal stability and effect on olein stability studies were performed. The results revealed that Olein oxidation time was reduced 17.2 and 4.2% in the presence of Isoespintanol and BHT, respectively. Thermogravimetric curves indicated higher thermal resistance for Isoespintanol than for BHT. Finally, cytotoxicity tests for Isoespintanol against murine macrophages revealed no effect on cell viability, indicating their possible use as a safe food additive.

 

Key words: Oxidative stabilization, isoespintanol, bht, antioxidant capacity, cytotoxicity, safe food additive.