Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3743

Full Length Research Paper

Metabolic profile of wistar rats after consumption of flour prepared with grains and fruits

Barbara Bucalem
  • Barbara Bucalem
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Barbara Geraldo Amaro
  • Barbara Geraldo Amaro
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Bruna Gomes Prado
  • Bruna Gomes Prado
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Julia Novacki
  • Julia Novacki
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Sandra Maria Barbalho
  • Sandra Maria Barbalho
  • Postgraduate Program in Structural and Functional Interactions in Rehabilitation (UNIMAR), Marília, SP, Brazil.
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Élen Landgraf Guiguer
  • Élen Landgraf Guiguer
  • Postgraduate Program in Structural and Functional Interactions in Rehabilitation (UNIMAR), Marília, SP, Brazil.
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Maricelma da Silva Soares de Souza
  • Maricelma da Silva Soares de Souza
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Manuela dos Santos Bueno
  • Manuela dos Santos Bueno
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Adriano Cressoni Araújo
  • Adriano Cressoni Araújo
  • Department of Medical Sciences, School of Medicine, University of Marília (UNIMAR), Avenida Higino Muzzi Filho, Marília, Brazil.
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Patrícia Cincotto dos Santos Bueno
  • Patrícia Cincotto dos Santos Bueno
  • Department of Biochemistry and Nutrition, Faculty of Food Technology of Marília, Avenida Castro Alves, Somenzari, Marília, São Paulo, Brazil.
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  •  Received: 25 January 2021
  •  Accepted: 25 June 2021
  •  Published: 31 July 2021

Abstract

The occurrence of chronic and degenerative diseases, such as obesity, diabetes, cardiovascular disease (CVD), and cancer is increasing sharply. In the last years, there has been an increase in interest in the consumption of foods with functional properties that are related to weight loss and disease prevention. For these reasons, this study aimed to evaluate the effects of flour prepared with grains and fruits on the metabolic profile of Wistar rats. Female rats were randomly divided into four groups: G1: control group; G2: Animals that received condensed milk and sugar; G3: Animals that received food supplemented with a mixture of powdered grains and fruits; G4: Animals that received condensed milk, sugar and rat food supplemented with a mixture of powdered grains and fruits. The authors results showed that the use of the flour of grains and fruits promoted a significant reduction in abdominal circumference, visceral fat, and triglycerides levels in the animals from G3 compared with G1. However, the use of the flour of grains and fruits can be beneficial in association with a balanced diet. When the association is carried out at the same time that there is the consumption of foods rich in sugars, the beneficial effects was not observed.

Key words: Obesity, grains, fruits, cardiovascular disease.