Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3830

Full Length Research Paper

Antioxidant activity, DNA damage protection and phenolic contents of Penthorum chinese Pursh

Xiao-Dong Xia1, Jing chen2, Sha Fan1, Xiao-Ling Gao1, Li-Hua Li1, Rong-Jun Chen1, Kai Zhong3, Hong Gao3, Isomaro Yamaguchi4 and Zheng-Jun Xu1*
1Rice Institute, Sichuan Agriculture of University, Chengdu 611130, PR China. 2Mianyang Jindi Hi-tech Seed Co. Ltd., Mianyang 621000, PR China. 3College of Light Industry, Textile and Food Engineering, Sichuan University, Chengdu 610065, PR China. 4Department of Applied Biological Chemistry, Graduate School of Agriculture and Life Sciences, University of Tokyo, Bunkyo-ku, Tokyo 113-8657, Japan.
Email: [email protected]

  •  Accepted: 11 June 2012
  •  Published: 31 July 2012

Abstract

The aim of this study was to determine the antioxidant potency of Penthorum chinesePursh (PCP) in vitro by using several assays, including 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity, 2,2’-azinobis-3-ethyl benzthiazoline-6-sulfonic acid (ABTS) radical scavenging activity, hydroxyl radical (·OH) scavenging activity and lipid peroxidation inhibitory activity. Meanwhile, the DNA damage protection by PCP was evaluated. PCP extracts showed the potent DPPH, ABTS and hydroxyl radicals scavenging activities and inhibited the lipid peroxidation. Moreover, PCP extracts exhibited DNA damage protective activity. The total phenols and flavonoids contents were determined and the phenolic compounds were analyzed by liquid chromatography-mass spectrometry (LC-MS). The results suggested that the medicinal function of PCP may be linked to the antioxidant activity.

 

Key words: Penthorum chinese Pursh, antioxidant, DNA damage protection, phenolic content.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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