Full Length Research Paper
IC50 for a novel antibiotic against mouse hepatoma H22 was determined to be 0.019 μg/mL by MTT assays. In KM mice bearing this kind of tumor that was treated by s.c. injection of antibiotic BS, marked cures were obtained. In terms of tumor weight, the treated/control=0.35. The conclusion is that BS merit further investigation as a potential anti-cancer candidate drug.
Key words: Bacillus subtilis, antibiotic, in vivo, in vitro, antitumor.
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