Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3778

Full Length Research Paper

Antioxidant and antimicrobial activities of essential oil of Skimmea laureola growing wild in the State of Jammu and Kashmir

Muhammad Irshad1, Shahid Aziz1*, Habib-ur-Rehman1, Muhammad Shahid2, Muhammad Naeem Ahmed1, Fiaz Aziz Minhas1 and Tufail Sherazi3
1Department of Chemistry, University of Azad Jammu and Kashmir, Muzaffarabad, 13100, Pakistan. 2Bioassay Section, PMBL, Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad- 38040, Pakistan. 3National Center of Excellence in Analytical Chemistry, University of Sindh, Jamshoro 76080, Pakistan.
Email: [email protected]

  •  Accepted: 27 December 2011
  •  Published: 09 March 2012


Fresh plant material of Skimmea laureola growing wild in the state of Azad Jammu and Kashmir was collected and subjected to Clevenger-type hydro distillation apparatus for essential oil extraction. The essential oils have been analyzed by gas chromatography mass spectrometry (GC-MS). Twenty components were identified, which yields about 96% of the total oils. The major components of the oils were linalalyl butyrate (35%), geraneol (9.5%), nerol (8.8%), citrolenol (7.7%) and ά-phallendrene (6.5%). Essential oil also exhibited good 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) radical scavenging activity showing 93.1% of inhibition and inhibition of peroxidation 45.02%. The essential oil of S. laureola showed appreciable antimicrobial activity against battery of selected species of bacteria and fungi, assessed by disc diffusion and measurement of minimum inhibition by micro dilution method. The plant was selected because of their reported medicinal importance in the indigenous system of medicines from ancient times and is abundantly available in various parts of Pakistan and particularly in State of Jammu and Kashmir.


Key wordsSkimmea laureola, essential oils composition, in vitro antimicrobial and antioxidant activity.