Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3823

Full Length Research Paper

Analysis of chemical composition of Chrysanthemum indicum flowers by GC/MS and HPLC

Liang-Yu Wu1, Hong-Zhou Gao1, Xun-Lei Wang1, Jian-Hui Ye1, Jian-Liang Lu2, Yue-Rong Liang1*
1 Zhejiang University Tea Research Institute, Hangzhou 310029, PR China. 2 The State Agriculture Ministry Laboratory of Horticulture Plant Growth Development and Quality Improvement, Hangzhou 310029, PR China.
Email: [email protected]

  •  Accepted: 15 February 2010
  •  Published: 04 March 2010


Chrysanthemum indicum flower is a traditional Chinese medicine with strong aroma and many previous studies focused on its essential oil. GC/MS and HPLC were used to determine its volatiles, flavonoids and flavonoid glycosides. Sixty three volatiles were detected and the abundant volatiles included 2,6,6-trimethyl-bicyclo[3.1.1]hept-2-en-4-ol, 2-(2,4-hexadiynylidene)-1,6-dioxaspiro[4.4]non-3-ene, germacrene D, á-neoclovene, eucalyptol, á-pinene. Ten flavonoids were identified. Quercitrin, myricetin and luteolin-7-glucoside were abundant flavonoids. The bioactivities of the abundant components in Chrysanthemum indicum flower were discussed. It is considered that Chrysanthemum indicumflower is a good source of natural quercitrin and myricetin, which is significant for the development of potential pharmaceuticals.


Key words: Chrysanthemum Morifolium, volatile, flavonoid, glycosides, GC-MS, HPLC.