Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3843

Full Length Research Paper

Isoliquiritigenin and β-sitosterol from Cissus polyantha Tuber Glig and Brandt

Y. M. Sani
  • Y. M. Sani
  • Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
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A. M. Musa
  • A. M. Musa
  • Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
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N. Tajuddeen*
  • N. Tajuddeen*
  • Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria.
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S. M. Abdullahi
  • S. M. Abdullahi
  • Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
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M. I. Abdullahi
  • M. I. Abdullahi
  • Department of Pharmaceutical and Medicinal Chemistry, Usmanu Danfodio University, Sokoto, Nigeria.
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U. U. Pateh
  • U. U. Pateh
  • Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
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A. Y. Idris
  • A. Y. Idris
  • Department of Pharmaceutical and Medicinal Chemistry, Ahmadu Bello University, Zaria, Nigeria.
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  •  Received: 02 March 2015
  •  Accepted: 09 August 2015
  •  Published: 17 September 2015

Abstract

Chemical investigation into the composition of Cissus polyantha tuber, a plant used in Northern Nigerian ethno medicine for managing inflammatory conditions and conjunctivitis has led to the isolation of a chalcone from the ethyl acetate and a steroid from the hexane soluble fractions of its methanol extract. The structures of these compounds were elucidated by extensive analysis of their spectroscopic data, including 1 and 2D nuclear magnetic resonance (NMR). This is the first report of the isolation of the compounds from the plant and they may be responsible for the previously reported anti-inflammatory effects.

   

Key words: Cissus polyantha, vitaceae, 2D nuclear magnetic resonance (NMR), chalcone, steroid.   

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This article is published under the terms of the Creative Commons Attribution License 4.0

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