Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3674

Full Length Research Paper

Biological properties and therapeutic applications of cannabidiol

Elanne Costa Glória
  • Elanne Costa Glória
  • Biodiversity and Biotechnology - BIONORTE, Federal University of Tocantins, NS 15 Avenue, 109 Norte, 77020-210 Palmas, TO, Brazil.
  • Google Scholar
Adriana Idalina Torcato de Oliveira
  • Adriana Idalina Torcato de Oliveira
  • General and Applied Microbiology Laboratory (LMGA), NS 15 Avenue, 109 Norte, 77020-210 Palmas, TO, Brazil.
  • Google Scholar
Juliana Fonseca Moreira da Silva
  • Juliana Fonseca Moreira da Silva
  • General and Applied Microbiology Laboratory (LMGA), NS 15 Avenue, 109 Norte, 77020-210 Palmas, TO, Brazil.
  • Google Scholar
Raphael Sanzio Pimenta
  • Raphael Sanzio Pimenta
  • Biodiversity and Biotechnology - BIONORTE, Federal University of Tocantins, NS 15 Avenue, 109 Norte, 77020-210 Palmas, TO, Brazil.
  • Google Scholar


  •  Received: 14 September 2019
  •  Accepted: 07 April 2020
  •  Published: 30 June 2020

References

Alledrone G, Pollastro F, Magagini G, Taglialatela-scafati O, Seegers J, Koeberle A, Werz O, Appendino G (2017). The bibenzyl canniprene inhibits the production of pro-inflammatory eicosanoids and selectively accumulates in some Cannabis sativa strains. Journal of Natural Products 80(3):731-734.
Crossref

 

Andre CM, Hausman JF, Guerriero G (2016). Cannabis sativa: The plant of the Thousand and one molecules. Frontiers in Plant Science 7(19):1-17.
Crossref

 

Basavarajappa BS (2017). Chapter 2 - Cannabinoid Receptors and their Signaling Mechanisms. In: Rodríguez EM, The Endocannabinoid System. Genetics, Biochemistry, Brain Disorders, and Therapy. pp. 25-62.
Crossref

 

Beale C, Broyd SJ, Chye Y, Suo C, Schira M, Galettis P, Martin JH, Yuce M, Solowiji N (2018). Prolonged Cannabidiol Treatment Effects on Hippocampal Subfield Volumes in Current Cannabis Users. Cannabis and Cannabinoid Research 3(1):94-107.
Crossref

 

Begg M, Pacher P, Batkai S, Osei-hyiaman D, Offertáler L, Mo FM, Liu J, Kunos (2005). Evidence of new cannabinoid receptors. Pharmacology and Therapeutics 106(2):133-145.
Crossref

 

Crippa JA, Guimarães FS, Campos AC, Zuardi AW (2018). Translational investigation of the therapeutic potential of Cannabidiol (CBD): Toward a New Age. Frontiers of Immunology, 9:2009.
Crossref

 

Hua T, Vemuri K, Pu M, Qu L, Han GW, Wu Y, Zhao S, Shui W, Li S, Korde A, Laprairie RB, Stahl E, Ho JH, Zvonok N, Zhou H, Kufareva I, Wu B, Zhao Q, Hanson MA, Bohn LM, Makriyannis A, Stevens RC, Liu ZJ (2016). Crystal structure of the Human Cannabinoid Receptor CB1. Cell 167(3):750-762.
Crossref

 

Jiang R, Yamaori S, Okamoto Y, Yamamoto I, Watanabe K (2013). Cannabidiol is a potent inhibitor of the Catalytic Activity of Cytochrome P4502C19. Drug Metabolism and Pharmacokinetics 28(4):332-338. 
Crossref

 

Kumar KK, Shalev-benami M, Robertson M, Hu H, Banister SD, Hollingsworth SA, Latorraca NR, Kato HE, Hilger D, Maeda S, Weis WI, Farrens DL, Dror RO, Malhotra SV, Kobilka BK, Skiniotis G (2019). Structure of a Signaling Cannabinoid Receptor 1-G Protein Complex. Cell 176(3):448-458.
Crossref

 

Lorenzen E, Sakmar TP (2019). Receptor Structures for a Caldron of Cannabinoids. Cell 176(3):409-411.
Crossref

 

Maroon J, Bost J (2018). Review of the neurological benefits of phytocannabinoids. Surgical Neurology International 9:91.
Crossref

 

Massi P, Solinas M, Cinquina V, Parolaro D (2013.) Cannabidiol as potential anticancer drug. British Journal of Clinical Pharmacology 75(2):303-312.
Crossref

 

Matsuda LA, Lolait SJ, Brownsten M, Young AC, Bonner TI (1990). Structure of a cannabinoid receptor and functional expression of cloned cDNA. Nature 346:561-564.
Crossref

 

Muller C, Morales P, Reggio PH (2019). Cannabinoid Ligands Targeting TRP Channels. Frontiers in Molecular Neuroscience 11:487.
Crossref

 

Munro S, Thomas KL, Abu-shaar M (1993). Molecular characterization of a peripheral cannabinoid receptor. Nature 365(6441):61-65.
Crossref

 

Pertwee RG (2008). The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: ∆9-tetrahydrocannabinol, cannabidiol and ∆9 -tetrahydrocannabivarin. British Journal of Pharmacology 153(2):199-215.
Crossref

 

Perucca E (2017). Cannabinoids in the Treatment of Epilepsy: Hard Evidence at Last? Journal of Epilepsy Research 7(2):60-76.
Crossref

 

Pellati F, Brighenti V, Sperlea JI, Marchetti L, Bertelli D, Benvenutri S (2018). New Methods for the Comprehensive Analysis of Bioactive Compounds in Cannabis sativa L. (hemp). Molecules 23(10):2639.
Crossref

 

Pollastro F, Minassi A, Fresu LG 2018. Cannabis phenolics and their bioactivities. Current Medicinal Chemistry 25(10):1160-1185.
Crossref

 

Romero-Sandoval EA, Fincham JE, Kolano AL, Sharpe BN, Alvarado-Vázquez PA (2018). Cannabis for Chronic Pain: Challenges and Considerations. Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 38(6):651-662.
Crossref

 

Wertz O, Seegers J, Schaible AM, Barz D, Koeberle A, Allegroned G, Pollastro F, Zampieri L, Grassi G, Appendino G (2014). Cannflavins from hemp sprouts, a novel cannabinoid-free hemp food product, target microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. Pharma Nutrition 2(3):53-60.
Crossref

 

Whittermore R, Knafl K (2005). The integrative review: updated methodology. Journal of Clinical Nursing 52(5):546-553.
Crossref

 

Zendulka O, Dovrtelová G, Nosková K, Turjap M, Sulcová A, Hanus L, Jurica J. (2016). Cannabinoids and Cytochrome P450 Interactions. Current Drug Metabolism 17(3):206-226.
Crossref