Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3702

Full Length Research Paper

Anticonvulsant activities of friedelan-3-one and n-dotriacontane both isolated from Harungana madagascariensis Lam (Hypericaceae) seeds extracts

Jordan Kache Signe
  • Jordan Kache Signe
  • Department of Chemistry, Faculty of Science, University of Buea, Box 63-Buea, Cameroon.
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Godfred Ayimele Aponglen
  • Godfred Ayimele Aponglen
  • Department of Chemistry, Faculty of Science, University of Buea, Box 63-Buea, Cameroon.
  • Google Scholar
James Mbah Ajeck
  • James Mbah Ajeck
  • Department of Chemistry, Faculty of Science, University of Buea, Box 63-Buea, Cameroon.
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Germain Sotoing Taiwe
  • Germain Sotoing Taiwe
  • Department of Zoology, Faculty of Science, University of Buea, Box 63-Buea, Cameroon.
  • Google Scholar


  •  Received: 15 June 2020
  •  Accepted: 28 August 2020
  •  Published: 31 October 2020

References

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Afieroho OE, Izontimi SS, Okoroafor DO., Caleb B (2012). Antibacterial and Phytochemical Evaluation of Harungana madagascariensis seeds. International Research Journal of Pharmacy 3(11):75-77.

 

Annafi OS, Umukoro S, Eduviere AT (2014). Evaluation of the Anticonvulsant and Anxiolytic Potentials of Methyl Jasmonate in Mice. Scientia Pharmaceutica 82:643-654.
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Bordoloi M, Surovi S, Prasanta KB, Bhaskor K, Partha PD, Purnajyoti DB, Subhas CD, Paruchuri GR (2017). Isolation, characterization and antifungal activity of very long chain alkane derivatives from Cinnamomum obtusifolium, Elaeocarpus lanceifolius and Baccaurea sapida. Journal of Molecular Structure 1142:200-210.
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Bum EN, Schmutz M, Meyer CM, Rakotonirina A (2001). Anticonvulsant Properties of the Methanolic Extract of Cyperus articulatus (Cyperaceae). Journal of Ethnopharmacology 76(2):145-150.
Crossref

 

Bum EN, Soudi S, Ayissi ER, Dong C, Laloulo NH, Maidawa F, Seke PFE, Nanga LD, Taiwe GS, Dimo T, Njifutie N, Rakotonirina A, Rakotonirina SV, Kamanyi A (2011). Anxiolytic Activity Evaluation of Four Medicinal Plants from Cameroon. African Journal of Traditional, Complementary and Alternative Medicine 8(5):130-139.
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Greenfield LJ (2013). Molecular Mechanisms of Antiseizure Drug Activity at GABAA Receptors. Seizure 22(8):589-600.
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Hui-Ling Z, Jian-Bo W, Yi-Tao W, Bao-Cai L, Cheng X, Jing H.,Peng L (2014). Medicinal Compounds with antiepileptic/anticonvulsant Activities. Journal of Epilepsia 55(1):3-16.
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Kouam SF, Ngadjui BT, Krohn K, Wafo P, Ajaz A, Choudhary MI (2005). Prenylatedanthronoid antioxidants from the stem bark of Harungana madagascariensis. Phytochemistry 66:1174-1179.
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Kouam SF, Yapna DB, Krohn K, Ngadjui BT, Ngoupayo J, Choudhary MI, Schulz B (2007). Antimicrobial prenylated anthracene derivatives from the leaves of Harungana madagascariensis. Journal of Natural Products 70(1):600-603.
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Lenta BN, Ngouela S, Boyom FF, Tantangmo F, Tchouya GRF, Tsamo E, Gut J, Rosenthal PJ, Connolly JD (2007). Anti-plasmodial activity of some constituents of the root bark of Harungana madagascariensis LAM. (Hypericaceae). Chemical and Pharmaceutical Bulletin 55(1):464-467.
Crossref

 

Nirupam D, Meenakshi D, Sushant KS (2012). An Overview on Antiepileptic Drugs. Journal of Drug Discovery and Therapeutics 6(4):178-193.

 

Noumi E, Fozi FL (2003). Ethnomedical Botany of Epilepsy Treatment in Fongo-Tongo Village, Western Province, Cameroon. Journal of Pharmaceutical Biology 41(5):330-339.
Crossref

 

Umukoro S, Itivere AO, Anthony TE (2013). Evaluation of the Effect of Jobelyn on Chemoconvulsants Induced Seizure in Mice. Journal of Basic and Clinical Neuroscience 4(2):19-23.

 

Wagner RG (2016). The Burden of Epilepsy Using population-based data to define the Burden and Model a Cost-effective Intervention for the Treatment of Epilepsy in Rural South Africa. Print and Media Umeå, Sweden, pp. 1-7.

 

Wahab A (2010). Difficulties in Treatment and Management of Epilepsy and Challenges in New Drug Development. Journal of Pharmaceuticals 3:2091-2110.
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Wahab OM (2015). Ethnomedicinal Antiepileptic Plants Used in Parts of Oyo and Osun States, Nigeria. Journal of Botany Research International 8(4):77-81.