Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3758

Full Length Research Paper

In vitro antiproliferative potential of Annona senegalensis Pers. and Allophylus africanus P Beauv. plant extracts against selected cancer cell lines

Emiliana Zacharia Biseko
  • Emiliana Zacharia Biseko
  • Department of Global Health and Biomedical Sciences, School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, P. O. Box 447, Arusha, Tanzania.
  • Google Scholar
Hulda Shaidi Swai
  • Hulda Shaidi Swai
  • Department of Global Health and Biomedical Sciences, School of Life Science and Bioengineering, Nelson Mandela African Institution of Science and Technology, P. O. Box 447, Arusha, Tanzania.
  • Google Scholar
Regina Wachuka Mbugua
  • Regina Wachuka Mbugua
  • Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute (KEMRI), P.O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar
Jecinta Wanjiru Ndung’u
  • Jecinta Wanjiru Ndung’u
  • Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute (KEMRI), P.O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar
Jean Chepng’etich
  • Jean Chepng’etich
  • Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute (KEMRI), P.O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar
Jeremiah Waweru Gathirwa
  • Jeremiah Waweru Gathirwa
  • Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute (KEMRI), P.O. Box 54840 00200, Nairobi, Kenya.
  • Google Scholar


  •  Received: 14 May 2019
  •  Accepted: 20 June 2019
  •  Published: 10 July 2019

References

Ajaiyeoba E, Falade M, Ogbole O, Okpako L, Akinboye D (2006). In vivo antimalarial and cytotoxic properties of Annona senegalensis extract. African Journal of Traditional, Complementary and Alternative Medicines 3(1):137-141.
Crossref

 

Ajuru MG, Williams LF, Ajuru G (2017). Qualitative and quantitative phytochemical screening of some plants used in ethnomedicine in the Niger delta region of Nigeria. Journal of Food and Nutrition Sciences 5(5):198-205. 
Crossref

 

Al-asady AAB, Suker DK, Hassan KK (2014). Cytotoxic and cytogenetic effects of Convolvulus arvensis extracts on rhabdomyosarcoma (RD) tumor cell line in vitro. Journal of Medicinal Plant Research 8(15):588-598. 
Crossref

 

Aslam MS, Naveed S, Ahmed A, Abbas Z, Gull I, Athar MA (2014). Side opinion about starvation based differential chemotherapy. Journal of Cancer Therapy 5:817-822. 
Crossref

 

Awa EP, Ibrahim S, Ameh DA (2012). GC/MS Analysis and antimicrobial activity of diethyl ether fraction of methanoolic extract from the stem bark of Annona senegalensis Pers. International Journal of Pharmaceutical Sciences and Research 3(11):4213-4218.

 

Balogun OS, Oladosu IA, Liu Z (2016). Fatty acid profile and in vitro biological activities of Allophylus africanus (P. Beauv). Journal of Herbs, Spices and Medicinal Plants 22(3):238-246. 
Crossref

 

Bandar H, Hijazi A, Rammal H, Hachem A, Saad Z, Badran B (2013). Techniques for the extraction of bioactive compounds from Lebanese urtica dioica. American Journal of Phytomedicine and Clinical Therapeutics 1(6):507-513. 

 

Baskar R, Lee KA, Yeo R, Yeoh K (2012). Cancer and radiation therapy : Current advances and future directions. International Journal of Medical Science 9(3):193-199. 
Crossref

 

Bézivin C, Tomasi S, Lohézic-Le Dévéhat F, Boustie J (2003). Cytotoxic activity of some lichen extracts on murine and human cancer cell lines. Phytomedicine 10:499-503. 
Crossref

 

Boik J (2001). Natural Compounds in Cancer Therapy (1 St). United State of Amerca. 

 

Chavan RB, Gaikwad DK (2016). The Ethnobotany, phytochemistry and biological properties of Allophylus species used in traditional medicine: a review. World Journal of Pharmacy and Pharmaceutical Sciences 5(11):664-682. 

 

Conklin KA (2004). Chemotherapy-associated oxidative stress: Impact on chemotherapeutic effectiveness. Integrative Cancer Therapies, 3(4):294-300. 
Crossref

 

Dhawan D Gupta J (2016). Comparison of different solvents for phytochemical extraction potential from Datura metel plant leaves. International Journal of Biological Chemistry 11:17-22. 
Crossref

 

Elansary HO, Szopa A, Kubica PB, Ekiert H, Ali HM, Elshikh MS, El-ansary DO (2018). Bioactivities of traditional medicinal plants in Alexandria. Evidence-Based Complementary and Alternative Medicine. Volume 2018, Article ID 1463579, pp 1-13.
Crossref

 

Fouche G, Cragg GM, Pillay P, Kolesnikova N, Maharaj VJ, Senabe J (2008). In vitro anticancer screening of South African plants. Journal of Ethnopharmacology 119:455-461. 
Crossref

 

Gberikon G, Adeoti I, Aondoackaa A (2015). Effect of ethanol and aqueous solutions as extraction solvents on phytochemical screening and antibacterial activity of fruit and stem bark extracts of Tetrapleura tetrapteraon, Streptococcus salivarus and Streptococcus mutans. International Journal of Current Microbiology and Applied Sciences 4(5):404-410.

 

Ghagane SC, Puranik SI, Nerli RB, Hiremath MB (2017). Evaluation of in vitro antioxidant and anticancer activity of Allophylus cobbe leaf extracts on DU-145 and PC-3 human prostate cancer cell lines. Cytotechnology 69:167-177
Crossref

 

Graham JG, Quinn ML, Fabricant DS, Farnsworth NR (2000). Plants used against cancer - an extension of the work of Jonathan Hartwell. Journal of Ethnopharmacology 73:347-377.
Crossref

 

Greenwell M, Rahman PKSM (2015). Medicinal Plants : Their use in anticancer treatment. International Journal of Pharma Sciences Research 6(10):4103-4112. 
Crossref

 

Kaur M, Agarwal C, Agarwal R (2009). Anticancer and cancer chemopreventive potential of grape seed extract and other. The Journal of Nutrition 139:1806S-1812S. 
Crossref

 

Khalid S, Shahzad A, Basharat N, Abubakar M, Anwar P (2018). Phytochemical screening and analysis of selected medicinal plants in phytochemistry and biochemistry. Journal of Phytochemistry and Biochemistry 2(1):2-4.

 

Kisangau DP, Lyaruu HVM, Hosea KM, Joseph CC (2007). Use of traditional medicines in the management of HIV / AIDS opportunistic infections in Tanzania : a case in the Bukoba rural district. Journal of Ethnobiology and Ethnomedicine 29(3):1-8. 
Crossref

 

Kitula AR (2007). Use of medicinal plants for human health in Udzungwa Mountains Forests: a case study of New Dabaga Ulongambi Forest Reserve. Journal of Ethnobiology and Ethnomedicine 7(3):1-4. 
Crossref

 

Koffi E, Sea T, Dodehe Y, Soro S (2010). Effect of solvent type on extraction of polyphenols from twenty three ivorian plants. Journal of Animal and Plant Sciences 5(3):550-558.

 

Kooti W, Servatyari K, Behzadifar M, Asadi-samani M, Sadeghi F, Nouri B, Marzouni HZ (2017). Effective medicinal plant in cancer treatment, Part 2 : Review study. Journal of Evidence-Based Complementary and Alternative Medicine 22(4):982-995. 
Crossref

 

Max PD, Bray F, Ferlay J, Pisani P (2005). Global cancer statistics, 2002. A Cancer Journal for Clinicians 55:74-108. 
Crossref

 

Mekonnen N, Abebe E (2017). Ethnobotanical knowledge and practices of traditional healers in Harar, Haramaya, Bati and Garamuleta, Eastern Ethiopia. Ethiopian Veterinary Journal 21(2):40. 
Crossref

 

Mustapha AA (2013). Annona senegalensis Persoon : A multipurpose shrub, its phytotherapic, phytopharmacological and phytomedicinal uses. International Journal of Science and Technology 2(12):862-865.

 

Napagoda MT, Sundarapperuma T, Fonseka D, Amarasiri S, Gunaratna P (2018). An Ethnobotanical study of the medicinal plants used as anti-inflammatory remedies in Gampaha district, Western province, Sri Lanka. Hindawi Scientifica 2:1-9.
Crossref

 

Ngo T, Scarlett CJ, Bowyer MC, Ngo PD, Vuong Q (2017). Impact of different extraction solvents on bioactive compounds and antioxidant capacity from the root of Salacia chinensis L. Journal of Food Quality, Vol. 2017, Article ID 9305047, pp. 1-8.
Crossref

 

Okoli CO, Onyeto CA, Akpa BP, Ezike AC, Akah PA, Okoye TC (2010). Neuropharmacological evaluation of Annona senegalensis leaves. African Journal of Biotechnology 9(49):8435-8444. 

 

Okoye TC, Akah PA, Ezike AC, Okoye MO, Onyeto CA, Ndukwu F, Ohaegbulam E, Ikele L (2012). Evaluation of the acute and sub-acute toxicity of Annona senegalensis root bark extracts. Asian Pacific Journal of Tropical Medicine 5(4):277-282. 
Crossref

 

Okoye TC, Akah PA, Nworu CS, Ezike AC (2014). Kaurenoic acid isolated from the root bark of Annona senegalensis induces cytotoxic and antiproliferative effects against PANC-1 and HeLa cells. European Journal of Medicinal Plants 4(5):579--589. 
Crossref

 

Prakash O, Kumar A, Kumar PA (2013). Anticancer potential of plants and natural products : a review. American Journal of Pharmacological Sciences 1(6):104-115. 
Crossref

 

Priya LM, Priya BK, Kotakadi VS, Josthna P (2015). Herbal and medicinal plants molecules towards treatment of cancer: a mini review. American Journal of Ethnomedicine 2(2). View

 

Rukunga GM, Gathirwa JW, Omar SA, Muregi FW, Muthaura CN, Kirira PG, Mungai GM, Kofi-Tsekpo WM (2009). Anti-plasmodial activity of the extracts of some Kenyan medicinal plants. Journal of Ethnopharmacology 121(2):282-285. 
Crossref

 

Senguttuvan J, Paulsamy S, Karthika K (2014). Phytochemical analysis and evaluation of leaf and root parts of the medicinal herb, Hypochaeris radicata L. for in vitro antioxidant activities. Asian Pacific Journal of Tropical Biomedicine 4:S359-S367. 
Crossref

 

Siegel RL, Miller KD, Jemal A (2018). Cancer statistics, 2018. Cancer Journal of Clinicians 68:7-30. 
Crossref

 

Snehlata K, Sheel R, Kumar B (2018). Evaluation of phytochemicals in polar and non-polar solvent extracts of leaves of Aegle marmelos (L). Journal of Biotechnology and Biochemistry 4(5):31-38. 

 

Sofidiya MO, Jimoh FO, Aliero AA, Afolayan AJ, Odukoya OA, Familoni OB (2012). Evaluation of antioxidant and antibacterial properties of six Sapindaceae members. Journal of Medicinal Plants Research 6(1):154-160. 
Crossref

 

Sowmya S, Lakshmidevi N (2013). Qualitative phytochemical analysis of nonpolar to polar solvent extracts of selected medicinal plants. International Journal of Current Research 5(12):3618-3621.

 

Thouri A, Chahdoura H, Arem A, El Hichri AO, Hassin R, Achour L (2017). Effect of solvents extraction on phytochemical components and biological activities of Tunisian date seeds (var . Korkobbi and Arechti ). BMC Complementary and Alternative Medicine 17(248):1-10. 
Crossref

 

Twentyman PR, Luscombe M (1987). A study of some variables in a tetrazolium dye (MTT) based assay for cell growth and chemosensitivity. British Journal of Cancer 56:279-285. 
Crossref

 

Wang S, Konorev EA, Kotamraju S, Joseph J, Kalivendi S, Kalyanaraman B (2004). Doxorubicin induces apoptosis in normal and tumor cells via. The Journal of Biological Chemistry 279(11):25535-25543. 
Crossref

 

WHO (World Cancer Report) (2014). The International Agency for Research on Cancer.

 

Yasser HEM (2016). Biochemistry and Analytical biochemistry in-vitro anti-cancer activity of extracts Dracaen Cinnabari Balf . F Resin from Socotra Island in Yemen Republic. Biochemistry and Analytical Biochemistry 5(3):1-17. 
Crossref