Aqueous extract of Persea americana leaves ameliorates alloxan-induced hyperglycaemia and hyperlipidaemia in rats
Decoctions of Persea americana Mill (Lauraceae) leaves are employed to manage diabetes mellitus among the Ibo communities of Eastern Nigeria. In this study, we studied the ameliorative effects of the aqueous extract of P. americana leaves (AEPAL) on alloxan-induced hyperglycaemia and hyperlipidaemia in Wistar rats. The oral median lethal dose (LD50) of AEPAL was determined in rats. The effects of extract on blood...
Phytochemical screening and In Vivo antimalarial activities of crude extracts of Lantana trifolia root and Premna oligotricha leaves in plasmodium berghei infected mice
Resistance of malaria parasites to several antimalarial drugs mandates the need for new compounds from affordable sources. Thus the current study was conducted to justify the traditional usage of Lantana trifolia roots and Premna oligotricha leaves to combat malaria. The powdered roots of Lantana trifolia and leaves of Premna oligotricha were macerated using 70% ethanol. Secondary metabolites present...