February 2015

Influence of extraction method on antibacterial activity of ethanolic extracts of Ocimum gratissimum L.

The aim of this study was to define whether novel extraction methods such as microwave and ultrasound could obtain the most effective ethanolic extracts of Ocimum gratissimum as antibacterial agents. These extracts were compared with respect to extractive yield, eugenol content, antibacterial activity and brine-shrimp (Artemia salina) toxicity with extracts obtained by the classical procedures of maceration and Soxhlet....

Author(s): Lenise de Lima Silva, Clarissa Giesel Heldwein, Luiz Gustavo Brenner Reetz, Rosmari Hörner, Diogo Pompéu de Moraes, Fábio Andrei Duarte, Érico Marlon de Moraes Flores, Renato Zanella, Ana Maria Soares Pereira and Berta Maria Heinzmann,  

February 2015

Identification of flavonol glycosides and in vitro photoprotective and antioxidant activities of Triplaris gardneriana Wedd

Triplaris gardneriana belongs to the family Polygonaceae, known for producing a number of biologically important molecules. The present study was aimed at identifying and quantify its total flavonoid content and determining the antioxidant and photoprotective potential of the plant’s leaves. The flavonoids present in the extract and fractions were analyzed using Liquid chromatography–mass spectrometry...

Author(s): Macedo Sandra Kelle Souza, Almeida Tamires dos Santos, Ferraz Christiane Adrielly Alves, Oliveira Ana Paula, Anjos Victor Hugo Almeida, Siqueira Filho José Alves, Araújo Edigênia Cavalcante da Cruz, Almeida Jackson Roberto Guedes da Silva, Silva Naiane Darklei Santos and Nunes Xirley Pereira  

February 2015

Pharmaco-toxic characterization of the aqueous extract from Pereskia grandifolia leaves

Medicinal plants are rich sources of bioactive compounds with potential for therapeutic, cosmetic and food use, and the species Pereskia grandifolia is widely used by low-income populations for nutritional and medicinal purposes. The objective of this study was to evaluate the pharmaco-toxic potential of the aqueous extract from P. grandifolia leaves, in order to obtain information on the safety of its use. P....

Author(s): Anderson Assaid Simão, Angelita Duarte corrêa, Thaís Cristina Lima de Carvalho, Pedro Henrique Souza Cesar, Carlos Henrique de Moura Oliveira and Silvana Marcussi  

February 2015

Assessment of the genotoxic and antigenotoxic potential of crude extracts and fractions of Schwartzia brasiliensis (Choisy) Bedell ex Giraldo-Cañas

Schwartzia brasiliensis (Marcgraviaceae) is a native Brazilian shrub species with neotropical distribution in shoal environments. Recent studies have revealed its medicinal potential for some human diseases; therefore, this study aimed to evaluate the genotoxic and antigenotoxic potential of extracts and fractions obtained from different organs of S. brasiliensis. To accomplish this, plant extracts at different...

Author(s): Mello G. S., De Mattos J. C. P., Amaral A. C. F., Amorim L. M. F., Caldeira-de-Araujo A. and Albarello N.