October 2012
Chemical composition of the plant Punica granatum L. (Pomegranate) and its effect on heart and cancer
In this report, the chemical composition and pharmacological properties of Punica granatum L. (Punicaceae) have been reviewed. In the past decade, numerous studies on the antioxidant, anticarcinogenic, and anti-inflammatory properties of pomegranate constituents have been published, focusing on treatment and prevention of cancer, cardiovascular disease, diabetes, dental conditions, erectile dysfunction,...
October 2012
Study on the extraction process and tyrosinase inhibition property of cichoric acid in Echinacea purpurea L.
Echinacea purpurea has become a commonly used herbal medicine because it contains various biologically active compounds, such as cichoric acid. Extraction conditions of cichoric acid from the flowers of E. purpurea L. were investigated through an orthogonal design of L9 (34) assay. For puriï¬cation, the extract was adsorbed on an AB-8 macroporous resin and eluted with 50% ethanol, then...
October 2012
Isolation of mangiferin and amyloid β-protein from n-hexane extract of roots of Wrightia tomentosa
The aim of this study is to identify and characterize the bioactive principles from the roots ofWrightia tomentosa. For isolation, the compound, the dried root powder of W. tomentosawas subjected to hot extraction with n-hexane to chromatography. Two compounds (WTRHF4 and WTRHF7) were isolated and purified by chloroform: toluene (7.5: 2.5) and chloroform: ethyl acetate (6: 4), respectively. The infra-red...
October 2012
Acute and subchronic toxicity evaluation of the hydroethanolic extract of germinated brown rice
The hydroethanolic extract obtained from a germinated brown rice (Oryza sativa L. indica) grown under conditions that favor high concentration of g-aminobutyric acid (GABA) was evaluated for acute and subchronic toxicities in rodents. Intragastric administration of this extract to Swiss albino mice of both sexes at a single dose of 2 g/kg body weight produced no toxicity signs during 7 days of observation. For...
October 2012
Antinociceptive effect of the ethanolic extract of Neoglaziovia variegata (Bromeliaceae) in mice
This study was carried out to evaluate the antinociceptive effects of ethanolic extract fromNeoglaziovia variegata (Nv-EtOH) in mice using models of nociception. The evaluation of antinociceptive activity was carried out by the acetic acid-induced writhing, formalin and hot plate tests. HPLC was used to determine the fingerprint chromatogram of the Nv-EtOH. In the acetic acid-induced writhing test, the Nv-EtOH...
October 2012
Antiulcerogenic activity of the aqueous fraction of Anacardium humile St. Hil (Anacardiaceae)
Anacardium humile St. Hil. is being used in traditional medicine to treat ulcer. The present work evaluated the mechanisms of action involved in the anti-ulcer properties of the aqueous fraction from leaves of A. humile (AHQ). Gastroprotection of A. humile was evaluated in ethanol and piroxicam models. Mechanisms of action such as mucus production, nitric oxide (NO), sulfhydryl...
October 2012
Efficacy of neem (Azadirachta indica A. Juss) callus and cells suspension extracts against three lepidopteron insects of cotton
The efficacy of various preparations of neem (Azadirachta indica A. Juss) (NCE1) and cells suspension extracts (NCE2) was evaluated against three cotton insects including pink bollworm (Pectinophora gossypiella), bollworm (Helicoverpa armigera) and leafworm (Spodoptera litura). The cotton leaves and medium size excised bolls were sprayed with different dilutions of NCE1 and NCE2 and 3rd instar larvae were...
October 2012
Immunomodulation by Stemona tuberosa ethanol extract in vitro and in ovalbumin-induced mouse asthma model
In the present study, we investigated the immunoregulatory effects of Stemona tuberose(ST) in an in vitro and in ovalbumin (OVA)-induced asthma model. Murine spleen cells were isolated from normal and OVA-treated mice and the cytokine levels from T-cells in supernatants were determined by enzyme-linked immunosorbent assay (ELISA). The results of the in vitro experiments indicated that ST...
October 2012
Antibacterial activity of some selected plants of family Zygophyllaceae and Euphorbiaceae
The antibacterial activity of the methanolic and n-hexane extracts of Fagonia cretica L., Peganum harmala L., Tribulus terrestris L., Chrozophora tinctoria (L.) Raf and Ricinus communis L., were investigated against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoni and Salmonella typhi. Phytochemical screening of the...
October 2012
Time and dosage effects of an endophytic fungal elicitor on the volatile oil production and physiology of Atractylodes lancea suspension cells
The effects of an endophytic fungal elicitor from Cunninghamella sp. (AL4) on the volatile oil production and defence responses of host plant Atractylodes lancea were investigated. The aim was to improve the capability of endophytic fungi resources in promoting medicinal plant secondary metabolites. The results showed that the endophytic fungal elicitor significantly stimulated volatile oil...
October 2012
Flavonoids from Taraxacum coreanum protect from radical-induced oxidative damage
The active components and protective activity of Taraxacum coreanum from oxidative stress under in vitro and cellular system using LLC-PK1 renal epithelial cells were investigated. T. coreanum was extracted with methanol (MeOH) and then fractionated into four different layers, n-hexane, trichloromethane (CHCl3), ethyl acetate (EtOAc), and n-butanol (n-BuOH). In...
October 2012
Isolation and spectral characterization of a new biaurone from Pongamia pinnata (L.) Pierre. (Fabaceae) pods
Pongamia pinnata (L.) Pierre. (Fabaceae) locally known as karanja is widely used to treat rheumatic pains, hypertension, bronchitis, whooping cough, and skin diseases. The present study attempts to isolate new compounds from a methanolic extract of P. pinnata pods. A novel light green, amorphous, powdered compound has been isolated from chloroform: methanol ratio (8.2:1.8) eluent through column...
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