February 2010
Coleus forskohlii – A comprehensive review on morphology, phytochemistry and pharmacological aspects
Coleus forskohlii is an important indigenous medicinal plant in India. It has been used in traditional Ayurvedic medicine for curing various disorders and this is the only source of the diterpenoid forskolin. Forskolin is used for the treatment of eczema, asthma, psoriasis, cardiovascular disorders and hypertension, where decreased intracellular cAMP level is believed to be a major factor in the...
February 2010
A survey on VAM association in three different species of Cassia and determination of antimicrobial property of these phytoextracts
Demands of traditional herbal medicines are increasing day by day over the world. Considering the growing demand of medicinal plants in curative treatments to our society and the role of VAM fungi in augmentation of the production of active secondary metabolites by the medicinal plants, the present work has been undertaken to survey the mycorrhizal status in three different species of Cassia viz, C. alata, C....
February 2010
Micropropagation of Plumbago zeylanica L. (Plumbaginaceae) in Ibadan, Southwestern, Nigeria
The root of Plumbago zeylanica is widely used by traditional Yoruba healers in Ibadan, Southwestern Nigeria, in the management and treatment of various infections and diseases. The plant is mainly harvested from the wild. The indiscriminate collection of the roots and non - cultivation of the plant has many implications for biodiversity. The plant is becoming scarce due to increasing demand for its use in...
February 2010
Simultaneous determination of 6 active components in traditional Chinese medicine “KANGXIN†tablets by RP-HPLC–DAD
A HPLC method was developed for simultaneous quantitative determination of the 6 compounds namely aloin, puerarin, genistein, daidzin, genistin and daidzein in “KANGXIN” tablets. The separation was achieved on a C18 column, a diode array detector at 260 nm and a mobile phase composed of acetonitrile and water under the gradient elution. Good linear relationships were obtained. The average recoveries...
February 2010
Microwave-assisted extraction of flavonoids from Chinese herb Radix Puerariae (Ge Gen)
Microwave-assisted extraction (MAE) technique was developed for the extraction of flavonoids from Radix Puerariae (FRP). Several influential parameters of the MAE procedure (ethanol concentration, solvent volume, microwave power and extraction time) were studied through single factor experiments and orthogonal experiment for the optimization of the extraction protocol. The optimal conditions of MAE were:...
February 2010
Chemotypic variations and phytotoxic studies of essential oils of endemic medicinal plant, Seriphidium kurramense, from Pakistan
Seriphidium kurramense is an endemic and economic medicinal plant growing in a small narrow valley of tribal region in Pakistan, Upper Kurram Agency, at Pakistan-Afghanistan border. GC-MS analysis of essential oils of S. kurramenseidentified 28 chemical constituents from 16 populations with two distinct chemotypes, A and B. Both chemotypes represented similar morphological features. Major chemical constituents...
February 2010
Antimicrobial activity of some traditional medicinal plants
The antimicrobial activity of the extracts of Andrographis paniculata Nees;Phyllanthus niruri Linn.; Terminalia bellerica Roxb.; Terminalia chebula Retz.; and Vitex negundo Linn., was studied against four gram negative and one gram positive bacteria. The results showed that the minimum inhibitory concentration (MIC) of P. niruri leaf extract was 50 µg/ml...
February 2010
Phytochemical screening, elemental analysis and acute toxicity of aqueous extract of Allium sativum L. bulbs in experimental rabbits
There seems to be little literature about the toxicity of the widely used garlic, which makes it important to investigate chemical elements as well as chemical compounds that could be present in garlic bulbs and their safety for human handlers and consumers. Phytochemical screening and elemental analysis of powdered bulb of Allium sativum L. and toxicological effects of its aqueous extract were...
February 2010
Detection of congenital anomalies in Mus musculus induced by crude leaf extracts of Goniothalamus amuyon (Blanco) Merr. and Alstonia macrophylla Wall. Ex G.Don
A significant portion of congenital malformations in newborn infants is caused by teratogenic exposure. By gaining information on the teratogenicity of a substance, it can be avoided especially during the crucial stages of pregnancy and by knowing the antiteratogenic effects of a substance; it can be used to counteract the effects of known teratogens. The objective of this study is to evaluate the teratogenic activities...
February 2010
Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro
In this article, we reported the isolation and characterization of Euphorbia factor L1 from Caper Euphorbia seed. The complete 1H and 13C NMR signals were assigned with the help of 1D, 2D NMR techniques. In addition, the anticancer activities of Euphorbia factor L1 were investigated. It exhibited potent cytotoxicity to KB, KBv200, MCF-7 and MCF-7/ADR cells with the...
February 2010
Proximate and nutrient composition of medicinal plants of humid and sub-humid regions in North-west Pakistan
The study was carried out to assess proximate composition and nutrientcontents of five medicinal plant species collected from Northwest Pakistan.Bupleurum falcatum and Valeriana officinalis belongs to humid regions, whileForsskalea tenacissima, Lavandula angustifolia and Otostegia limbata belongs to sub-humid regions. Proximate analysis (total protein,...
February 2010
Chemical composition of leaf oil of Nigerian grown Aspilia africana C. D. Adams
Pulverized leaves of Aspilia africana afforded oil in the yield of 0.08% v/w. GC, GC/MS analyses of the oil revealed the abundance of sesquiterpenes (57.5%), with α-cubebene (31.1%) as the major component. Copaene (7.0%) and β-caryophyllene (4.8%) existed in appreciable quantities. Predominant monoterpenes were: α-pinene (6.7%), α-thujene (5.1%) and car-3-ene (5.0%). Key...
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