January 2008
Toxicopathological effects of Guiera senegalensis extracts in wistar albino rats
Toxicity of methanolic and water extracts of the plant Guiera sengalensis has been tested on rats. The methanolic extract was injected intramuscularly while the water extract was given orally. Rats receiving 1000 and 500 mg/kg/day of the methanolic extract died within one week. The 250 mg/kg/day dose resulted in enlargement of the liver and kidneys, although body weights of the treated rats were not...
January 2008
In vitro rat lymphocyte proliferation induced by Ocinum basilicum, Persea americana, Plantago virginica, and Rosa spp. extracts
Medicinal plants have been used for centuries and have become part of complementary medicine worldwide because of their potential health benefits. Some of their metabolites have been successfully used directly in the treatment and prevention of infectious diseases and cancer, or indirectly by...
January 2008
Wound healing and antibacterial activities of the extract of Dissotis theifolia (Melastomataceae) stem formulated in a simple ointment base
In this study, we investigated a herbal ointment containing Dissotis theifoliaextract for wound healing and antibacterial activities against clinical wound isolates of Staphylococcus aureus and Pseudomonas aeruginosa. The ointment batches containing different concentrations of the D. theifolia extract was applied topically to both infected and uninfected wounds inflicted on rats and the...
January 2008
Antihepatotoxic effect of Picrorhiza kurroa on mitochondrial defense system in antitubercular drugs (isoniazid and rifampicin)-induced hepatitis in rats
Oxidative stress is one of the mechanisms with a central role involved in the pathogenesis of antitubercular drugs (isoniazid and rifampicin)-induced hepatitis. In the present study the antihepatotoxic effect of the ethanol extract of Picrorhiza kurroa rhizomes and roots (PK) on liver mitochondrial antioxidant defense system in antitubercular drugs (isoniazid and rifampicin)-induced hepatitis in rats has been...
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