Journal of
Physiology and Pathophysiology

  • Abbreviation: J. Physiol. Pathophysiol.
  • Language: English
  • ISSN: 2141-260X
  • DOI: 10.5897/JPAP
  • Start Year: 2010
  • Published Articles: 49

Full Length Research Paper

Changes in haematological parameters of children aged 5 to 18 years in Abidjan, Côte d’Ivoire

Mathieu Nahounou Bleyere1*, André Brou Konan2, Augustin Kouao Amonkan2, Hélène Delisle3, Duni Sawadogo4, Jacques Yao Datte2 and Paul Angoué Yapo1
  1Laboratory of Physiology, Pharmacology and Phytotherapy (Training and Research Unit of Natural Sciences)/Nangui Abrogoua University, 02 BP 801 Abidjan 02, Côte d’Ivoire. 2Laboratory of nutrition and pharmacology (Unit Training and Research of Biosciences)/Félix Houphouët-Boigny University, 22 BP 582 Abidjan 22, Côte d’Ivoire. 3Department of Nutrition/Laboratory of Nutrition (Faculty of Medecine)/University of Montreal (Canada), CP 6128 ucc. Centre-ville, Montréal Qc Canada H3C 3J7, Canada. 4Laboratoire of haematology (Training and Research Unit of the Biological and Pharmaceutical Sciences)/Félix Houphouët-Boigny University, 21 BP 632 Abidjan 21, Côte d’Ivoire.
Email: [email protected]

  •  Accepted: 20 February 2013
  •  Published: 30 March 2013

Abstract

 

The Millennium Development Goals include an aspect of children's health. The main purpose of this study was to indicate possible changes in different blood cells on one hand and secondly to establish standards of various parameters of the counts in the blood. The study involved 1,157 children aged 5 to 18 years in four selected municipalities of Abidjan. Blood sampling was done fasting in the morning, between 7 and 9 h for each child to complete blood count. In addition, an electrophoretic profile of each subject was performed from a volume of red blood cells. All observed haematological parameters in children was analyzed by a program Statistical Statsoft Windows version 7.1. The results of the study showed that all haematological parameters in children aged 5 to 18 years did not differ significantly by gender (p > 0.05) except for the red blood cells and thrombocytes. The red blood cells were significantly (p < 0.05) higher among boys (4.9 ± 0.02 × 1012/L) than girls (4.4 ± 0.02 × 1012/L). In contrast, girls (297.5 ± 5.4 × 106/L) in our study showed a significant increase in thrombocytes when compared with boys (285.6 ± 5.6 × 106/L). Morever, significant differences were observed between groups of children according to their age for red blood cells, hemoglobin, hematocrit and thrombocytes. Our investigations in these children have reported normal haematological status (11.5%) against 88.5% for abnormal haematological status. Furthermore, in all, 47% of the children presented with anaemia. The prevalence of studied children with normal hemoglobin was 84.4% against 15.6% for abnormal hemoglobin. Haematological parameters of the selected children are degraded in all. Nutrition, infectious and inflammatory syndromes and hemoglobinopathies could be the main factors.

 

Key words: Children, haematological status, anaemia, hemoglobin phenotype, Côte d'Ivoire.