Journal of
Physiology and Pathophysiology

  • Abbreviation: J. Physiol. Pathophysiol.
  • Language: English
  • ISSN: 2141-260X
  • DOI: 10.5897/JPAP
  • Start Year: 2010
  • Published Articles: 45

Full Length Research Paper

Oxytocin ameliorates the deleterious effect of pain in adult male rats

Nessren M. Abd el-Rady
  • Nessren M. Abd el-Rady
  • Department of Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Google Scholar
Omyma G. Ahmed
  • Omyma G. Ahmed
  • Department of Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Google Scholar
Ebtihal A. Abd El-Aziz
  • Ebtihal A. Abd El-Aziz
  • Department of Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Google Scholar
Ayman M. Osman
  • Ayman M. Osman
  • Department of Anesthesia and Intensive Care, Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Google Scholar
Amel Taha
  • Amel Taha
  • Department of Histology. Faculty of Medicine, Assiut University, Assiut, Egypt.
  • Google Scholar


  •  Received: 18 August 2016
  •  Accepted: 14 September 2016
  •  Published: 31 January 2017

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Schorscher-Petcu A, Sotocinal S, Ciura S, Dupre A, Ritchie J, Sorge RE, Crawley JN, Hu SB, Nishimori K, Young LJ, Tribollet E (2010). Oxytocin-induced analgesia and scratching are mediated by the vasopressin-1A receptor in the mouse. J. Neurosci. 30:8274-8284.
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Yaksh TL, Hobo S, Peters C, Osborn KG, Richter PJ Jr, Rossi SS, Grafe MR, Eisenach JC (2014). Preclinical Toxicity Screening of Intrathecal Oxytocin in Rats and Dogs. Anesthesiology 120(4):951-61.
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Yang J, Liang JY, Zhang XY, Qiu PY, Pan YJ, Li P, Zhang J, Hao F, Wang DX, Yan FL (2011c). Oxytocin, but not arginine vasopressin is involving in the antinociceptive role of hypothalamic suproptic nucleus. Peptides 32(5):1042-1046.
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Yang Y, Wen L,Cao Y, Bao L (2006). Through central arginine vasopressin, not oxytocin and endogenous opiate peptides, glutamate sodium induces hypothalamic paraventricular nucleus enhancing acupuncture analgesia in the rat. Neurosci. Res. 54(1):49-56.
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