Journal of
Public Health and Epidemiology

  • Abbreviation: J. Public Health Epidemiol.
  • Language: English
  • ISSN: 2141-2316
  • DOI: 10.5897/JPHE
  • Start Year: 2009
  • Published Articles: 511

Article in Press

Knowledge, Practice and Associated Factors towards Adverse Drug Reaction reporting among nurses working in district Hospitals, Northwest Ethiopia.


  •  Received: 28 November 2018
  •  Accepted: 28 November 2018
Background- Adverse Drug Reaction (ADR) is any noxious, unintended and undesired effect of a drug which occurs at doses normally used in humans for prophylaxis, diagnosis, or therapy of disease or the modification of the physiological functions. Adverse drug reactions lead to a number of medical and economical consequences. Objective: To assess knowledge, practice and associated factors towards Adverse Drug Reaction reporting among Nurses working in District Hospitals Northwest Ethiopia 2016. Methods: Institutional based cross sectional study was conducted from April 2- April 29, 2016 at six district Hospitals in North-west Ethiopia. Data were collected by pretested, validated, self administered questionnaire then entered using EPI Info V. 7.0 and imported to SPSS V. 20 for possible statistical analysis and association. Multivariate regression analysis was used to examine the association between the Adverse Drug Reaction reporting and associated factors. Significance was obtained at 95% CI and p< 0.05 and odds ratio is used to measure strength of association. Result: A total of 314 nurses were responded by making response rate of 96.3%. Out of this 53.5% were male and the mean ages were 25.9± 2.5. Among the study participants 101(32.2%) and 41(13.1%) of Nurses were knowledgeable and good practice respectively. Training [AOR= 3.285(1.136, 9.501)], Not knowing how to report [AOR=0.249(0.085, 0.728)], unavailability of reporting form [AOR= 0,190 (0.070, 0.518)] and reporting will generate extra work [AOR= 0.266(0.082, 0.780)] were variables significantly associated with nurses reporting practice of ADRs. Conclusion: Overall, this study revealed that knowledge of nurses were low and had poor practice towards ADRs reporting in District Hospitals Northwest Ethiopia. Training, level of education, not knowing how to report, unavailability of reporting form and concern that reporting will generate extra work were found to be associated.