Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 226

Full Length Research Paper

Effect of Ethiopian high land green tea (Camellia sinensis) leaf extract on highly active anti-retroviral therapy induced dyslipidemia in Albino Wistar rats

Tesaka Wondimnew
  • Tesaka Wondimnew
  • Biomedical Sciences Unit, College of Health Sciences, Jimma University, P. O. Box 378, Jimma, Ethiopia.
  • Google Scholar
Natesan Gnanasekaran
  • Natesan Gnanasekaran
  • Department of Medical Biochemistry, School of Medicine, College of Health Sciences, Addis Ababa University, P. O. Box 9086, Addis Ababa, Ethiopia.
  • Google Scholar
Solomon Genet
  • Solomon Genet
  • Department of Medical Biochemistry, School of Medicine, College of Health Sciences, Addis Ababa University, P. O. Box 9086, Addis Ababa, Ethiopia.
  • Google Scholar


  •  Received: 28 December 2017
  •  Accepted: 22 February 2018
  •  Published: 30 April 2018

References

Abebe M, Kinde S, Belay G, Gebreegziabhier A, Challa F, Gebeyehu T, Nigussie P, Tegbaru B (2014). Antiretroviral treatment associated hyperglycemia and dyslipidemia among HIV infected patients at Burayu Health Center, Addis Ababa, Ethiopia: a crosssectional comparative study. BMC Res. Notes 7:380-387.
Crossref

 

Andrea M, Sabrina C, Barbara R, Daniela F, Giuseppe P, Eleonora D, Franco B, Stefano F (2010). The Bile Acid Sensor FXR Protects against Dyslipidemia and Aortic Plaques Development Induced by the HIV Protease Inhibitor Ritonavir in Mice. PLoS ONE 5:e13238
Crossref

 

Arshad HR, Fahad MA, Khaled SA, Saleh SA, Masood AK (2015). Implications of green tea and its constituents in the prevention of cancer via the modulation of cell signalling pathway. BioMed. Res. Int. pp. 1-12.

 

Balentine DA, Wiseman SA, Bouwens LC (1997). The chemistry of tea flavonoids. Crit. Rev. Food Sci. Nutr. 37:693-704.
Crossref

 

Bhaskaran K, Hamouda O, Sannes M, Boufassa F, Johnson AM, Lambert PC, Porter K CASCADE Collaboration (2008). Changes in the risk of death after HIV seroconversion compared with mortality in the general population. JAMA 300:5-59.
Crossref

 

Bursill CA, Abbey M, Roach PD (2007). A green tea extract lowers plasma cholesterol by inhibiting cholesterol synthesis and upregulating the LDL receptor in the cholesterol-fed rabbit. Atherosclerosis 193:86-93.
Crossref

 

Chacko SM, Thambi PT, Kuttan R, Nishigaki I (2010). Beneficial effects of green tea: a literature review. Chin. Med. 5:13-19.
Crossref

 

Chantry CJ, Hughes MD, Alvero C, Cervia JS, Meyer WA (2008). Lipid and glucose alterations in HIV-infected children beginning antiretroviral therapy. Pediatrics 122:129-38.
Crossref

 

Chen Qi (2006). Chinese traditional medicine pharmacological research methodology. Guangzhou, Peoples's Medical Publishing Company.

 

Ebrahimzadeh MA, Nabavi SM, Nabavi SF, Eslami B (2009). Free radical scavenging ability of methanolic extract of Hyoscyamus squarrosus leaves. Pharmacologyonline 2:796-802.

 

Feeney ER, Mallon PW (2011). HIV and HAART associated dyslipidemia. Open Cardiovasc. Med. J. 5:49-63.
Crossref

 

Fisher SD, Miller TL, Lipshultz SE (2006). Impact of HIV and highly active antiretroviral therapy on leukocyte adhesion molecules, arterial inflammation, dyslipidemia and atherosclerosis. Atherosclerosis 185:1-11.
Crossref

 

Flint OP, Lubinski LJ, Parker RA, Noor M (2005). Comparative effects of atazanavir versus other HIV protease inhibitors on glucose and amino acid stimulated insulin secretion. Antivir. Ther. 10:32.

 

Govarthanan M, Rajinikanth R, Kamala-Kannan S, Selvankumar T (2015). A comparative study on bioactive constituents between wild and in vitro propagated Centella asiatica. Genet Eng. Biotechnol. J. 13(1):25-29.
Crossref

 

Gsponer T, Petersen M, Egger M, Phiri S, Maathuis MH, Boulle A (2012). The causal effect of switching to secondline ART in programmes without access to routine viral load monitoring. AIDS 26:57-65.
Crossref

 

Gyamfi MA, Yonamine M, Aniya Y (1999). Free radical scavenging action of medicinal herbs from Ghana Thonningia sanguine on experimentally induced liver injuries. Gen. Pharmacol. 32:661-67.
Crossref

 

Koo SI, Noh SK (2007). Green tea as inhibitor of the intestinal absorption of lipids: potential mechanism for its lipid-lowering effect. J. Nutr. Biochem. 18:179-183.
Crossref

 

Lee GA, Rao MN, Grunfeld C (2005). The effects of HIV protease inhibitors on carbohydrate and lipid metabolism. Curr. HIV/AIDS Rep. 2:39-50.
Crossref

 

Loest HB, Noh SK, Koo SI (2002). Green tea extract lowers the lymphatic absorption of cholesterol and a-tocopherol in ovariectomized rats. J. Nutr. 132:1282-1288.
Crossref

 

Muramatso K, Fukuyo M, Hara Y (1986). Effect of green tea catechins on plasma cholesterol level in cholesterol-fed rats. J. Nutr. Sci. Vitaminol. 32:613-622.
Crossref

 

Parker RA, Flint OP, Mulvey R, Elosua C, Wang F (2005). Endoplasmic reticulum stress links dyslipidemia to inhibition of proteasome activity and glucose transport by HIV protease inhibitors. Mol. Pharmacol. 67:1909-1919.
Crossref

 

Purnell JQ, Zambon A, Knopp RH, Pizzuti DJ, Achari R, Leonard JM, Locke C, Brunzell JD (2000). Effect of ritonavir on lipids and post-heparin lipase activities in normal subjects. AIDS 14:51-57.
Crossref

 

Rabia SA, Masood SB, M Tauseef Sultan, Zarina M, Shakeel A, Saikat D, Vincenzo De Feo, Muhammad ZUH (2015). Preventive role of green tea catechins from obesity and related disorders especially hypercholesterolemia and hyperglycemia. J. Transl. Med. 13:79.
Crossref

 

Rani R, Nagpal D, Gullaiya S, Madan S, Agrawal SS (2014). Phytochemical, Pharmacological and Beneficial Effects of Green Tea. IJPPR 6:420-426.

 

Riddle TM, Kuhel DG, Woollett LA, Fichtenbaum CJ, Hui DY (2001). HIV protease inhibitor induces fatty acid and sterol biosynthesis in liver and adipose tissues due to the accumulation of activated sterol regulatory element-binding proteins in the nucleus. J. Biol. Chem. 276(40):37514-37519.
Crossref

 

Rouleau D, Fortin C, Trotier B, Lalonde R, Lapointe N, Cote P (2011). Antiretroviral therapy for adults infected with HIV. Guidelines for health care profesionals from Quebec HIV care committee. Can. J. Infect Dis. Med. Microbiol. 22:52-60.
Crossref

 

Shafran SD, Mashinter LD, Roberts SE (2005). The effect of low-dose ritonavir monotherapy on fasting serum lipid concentrations. HIV Medicine 6:421-425.
Crossref

 

Shrestha S, Ehlers SJ, Lee JY, Fernandez ML, Koo SI (2009). Dietary green tea extract lowers plasma and hepatic triglycerides and decreases the expression of sterol regulatory element-binding protein-1c mRNA and its responsive genes in fructose-fed, ovariectomized rats. J. Nutr. 139(4):640-645.
Crossref

 

Soler‐Rivas C, Espín JC, Wichers HJ (2000). An easy and fast test to compare total free radical scavenger capacity of foodstuffs. Phytochem. Anal. 11(5):330-338.
Crossref

 

Sprinz E, Lazzaretti RK, Kuhmmer R, Ribeiro JP (2010). Dyslipidemia in HIV-infected individuals. Br. J. Infect Dis. 14:575-588.
Crossref

 

Tassiopoulos K, Williams P, George R, Marilyn C, James O, John F (2008). Association of Hypercholesterolemia Incidence with Antiretroviral Treatment, Including Protease Inhibitors, Among Perinatally HIV-Infected Children. J. AIDS. 47:607-614.
Crossref

 

Tran H, Robinson S, Mikhailenko I, Strickland DK (2003). Modulation of the LDL receptor and LRP levels by HIV protease inhibitors. J. Lipid Res. 44(10):1859-1869.
Crossref

 

Wang S, Noh SK, Koo SI (2006a). Epigallocatechin gallate and caffeine differentially inhibit the intestinal absorption of cholesterol and fat in ovariectomized rats. J. Nutr. 136:2791-2796.
Crossref

 

Wang S, Noh SK, Koo SI (2006b). Green tea catechins inhibit pancreatic phospholipase A2 and intestinal absorption of lipids in ovariectomized rats. J. Nutr. Biochem. 17:492-498.
Crossref

 

Xu JZ, Yeung SYV, Chang Q, Huang Y, Chen ZY (2004). Compar-ison of antioxidant activity and bioavailability of tea epicatechins with their epimers. Br. J. Nutr. 91:873-881.
Crossref

 

Zaveri NT (2006). Green tea and its polyphenolic catechins: Medicinal uses in cancer and non-cancer applications. Life Sci. 78:2073-2080.
Crossref