Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 224

Full Length Research Paper

African medicinal plant derived products as therapeutic arsenals against multidrug resistant microorganisms

Assob Jules Clement Nguedia*
  • Assob Jules Clement Nguedia*
  • Department of Biomedical Sciences, Faculty of Health Sciences, University of Buea, Cameroon. P. O. Box 63 Buea, Cameroon
  • Google Scholar
Nsagha Dickson Shey
  • Nsagha Dickson Shey
  • Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Cameroon. P. O. Box 63 Buea Cameroon.
  • Google Scholar


  •  Received: 16 November 2013
  •  Accepted: 05 May 2014
  •  Published: 30 June 2014

References

Aiyegoro OA, Afolayan AJ, Okoh AI (2009). Synergistic interaction of Helichrysum pedunculatum leaf extracts with antibiotics against wound infection associated bacteria. Biol. Res. 42:327-338.
Crossref
 
Assob JCN, Kamga HLF, Nsagha DS, Njunda AL, Nde PF, Asongalem AE Njouendou AJ, Sandjon B, Penlap VB (2011). Antimicrobial and toxicological activities of five medicinal plant species from Cameroon Traditional Medicine. BMC Compl. Alter. Med. 11:70.
Crossref
 
Assob JCN, Kamga HLF, Nsagha DS, Njunda AL, Nde PF, Asongalem AE Njouendou AJ, Sandjon B, Penlap VB (2011). Antimicrobial and toxicological activities of five medicinal plant species from Cameroon Traditional Medicine. BMC Compl. Alter. Med. 11:70.
Crossref
 
Aladesanmi AJ, Iwalewa EO, Adebajo AC, Akinkunmi EO, Taiwo BJ, Olorunmola FO, Lamikanra A (2007). Antimicrobial and Antioxidant Activities of Some Nigerian Medicinal Plants. Afr. J. Tradit. CAM. 4 (2): 173 – 184.
 
Balagon MF, Cellona RV, Abalos RM, Gelber RH, Saunderson PR (2010). The efficacy of a four-week, ofloxacin-containing regimen compared with standard WHO-MDT in PB leprosy. Lepr. Rev. 81:27–33.
Pubmed
 
Bawm BS, Matsuura H, Elkhateeb A, Nabeta K, Subeki NN, Oku Y, Katakura K (2008). "In vitro Antitrypanosamal activities of quassinoid compounds from the fruits of a medicinal plant, Brucea javanica," Vet. Parasitol. 158(4):288- 294.
Crossref
 
Bickii J, Feuya GRT, Tchouankeu JC, Tsamo E (2007). The antiplasmodial agents of the stem bark of Entandrophragma angolense (Meliaceae). Afr. J. Trad. CAM. 4(2):135-139.
 
Bisi-Johnson MA, Chikwelu LO, Eloff J, Bolorunduro BS, Kamaldeen B, Vasaikar S, Adefisoye MA (2012). Can herbal remedies be the answer to multidrug resistance? Profile of drug resistance in Salmonella species in Eastern Cape, South Africa. J. Exp. Integr. Med. 2(2):147-153.
 
Camacho MDR, Phillipson JD, Croft SL, Solis PN, Marshall SJ, Ghazanfar SA (2003). Screening of plant extracts for antiprotozoal and cytotoxic activities. J. Ethnopharmacol. 89(2-3):185-191.
Crossref
 
Chitemerere TA, Mukanganyama S (2011). In vitro antimicrobial activity of some selected medicinal plants from Zimbabwe. Afr. J. Plant Sci. Biotech. 5(1):1-7.
 
Daferera DJ, Ziogas BN, Polissiou MG (2003). The effectiveness of plant essential oils on the growth of Botrytis cinerea, Fusarium sp. and Clavibacter michiganensis subsp. michiganensis. Crop. Prot. 22:39-44.
Crossref
 
Djeussi DE, Noumedem JAK, Seukep JA, Fankam AG, Voukeng IK, Tanke SK, Nkuete HAL, Kuete V (2013). Antibacterial activities of selected edible plants extracts against multidrug-resistant Gram-negative bacteria. BMC Compl. Alter. Med. 13:164.
Crossref
 
Dzomba P, Muchanyereyi N (2012). Potential Antimicrobial Plant Extract Based Therapeutics from Temnocalyx obavatus Roots. Eur. J. Med. Plants 2(3):209-215.
Crossref
 
Ehata MT, Phuati AM, Lumpu SN, Munduku CK, Phongi DB, Lutete, GT, Kabangu OK, Kanyanga RC, Matheeussen A (2012). In vitro antiprotozoal and cytotoxic activity of the aqueous extract, the 80% methanol extract and its fractions from the Seeds of Brucea sumatrana Roxb. (Simaroubaceae) growing in Democratic Republic of Congo. Chin. Med. 3:65-71.
Crossref
 
Elkhateeb A, Yamasaki M, Maede M, Katakura K, Nabeta K, Matsuura H (2008). "Anti-Babesial Quassinoids from the Fruits of Brucea javanica." Nat. Prod. Commun. 3(1):1-4.
 
Ganfon H, Bero J, Tchinda AT, Gbaguidi F, Gbenou J, Moudachirou M, Frédérich M, Quetin-Leclercq J (2012). Antiparasitic activities of two sesquiterpenic lactones isolated from Acanthospermum hispidum D.C. J. Ethnopharmacol. 141(1):411-417.
Crossref
 
Gangoué-Piéboji P, Eze N, Djintchu AN, Ngameni B, Tsabang N, Pegnyemb D E, Biyiti L, Ngassam P, Koulla-Shiro S, Moreno G (2009). The in-vitro antimicrobial activity of some traditionally used medicinal plants against beta-lactam-resistant bacteria. Infect. Dev. Ctries. 3(9):671-680.
 
Htut ZW (2009). Artemisinin resistance in Plasmodium falciparum malaria. N. Engl. J. Med. 361:1807-1808.
Crossref
 
Iwu MM, Duncan AR, Okunji CO (1999). New Antimicrobials of Plant Origin. New antimicrobials of plant origin. In: J. Janick (ed.), Perspectives on new crops and new uses. ASHS Press. pp. 457–462.
 
Iruka NO, Sosa A (2008). Antibiotic resistance in Africa- Discerning the enemy and plotting a defense. http://www.tufts.edu/med/apua/about_issue/africahealth.pdf
 
Kim HS, Shibata Y, Ikemoto NK, Ishizuka N, Murakami Y, Sugimoto N, Kobayashi M, Wataya Y (2000). Potent in vivo antimalarial activity of 3,15-Di-O-ace- tylbruceolide against Plasmodium berghei Infection in Mice." Parasitol. Int. 48(3):271-274.
Crossref
 
Konaté K, Hilou A, Mavoungou JF, Lepengué AN, Souza A, Barro N, Datté JY, M'Batchi B, Nacoulma OG (2012). Antimicrobial activity of polyphenol rich fractions from Sida alba L. (Malvaceae) against co- trimoxazol resistant bacteria strains. Ann. Clin. Microbiol. Antimicrob.11:5.
Crossref
 
Korir RK, Mutai C, Kiiyukia C, Bii C (2012). Antimicrobial activity and safety of two medicinal plants traditionally used in Bomet District of Kenya. Res. J. Med. Plant 6:370-382.
Crossref
 
Kuete V, Efferth T (2010). Cameroonian medicinal plants: pharmacology and derived natural products. Frontiers Pharmacol. 123:1-19.
 
Kuete V, Kamga J, Sandjo LP, Ngameni B, Poumale, HMP, Ambassa P, Ngadjui BT (2011). Antimicrobial activities of the methanol extract, fractions and compounds from Ficus polita Vahl. (Moraceae). BMC Complement. Alter. Med. 11:6.
Crossref
 
Kuete V, Ngameni B, Mbaveng AT, Ngadjui B, Marion MJJ, Lall N (2010). Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and anti-reverse transcriptase activities. Acta Trop. 116:100–104.
Crossref
 
Kiessoun K, Hilou A, Mavoungou JF, Lepengué AN, Souza A, Barro Datté N, M'Batchi JBY, Nacoulma GO (2012). Antimicrobial activity of polyphenol rich fractions from Sida alba L. (Malvaceae) against co-trimoxazol resistant bacteria strains. Ann. Clin. Microbiol. Antimicrob. 11:5.
Crossref
 
Kuete V, Efferth T (2010). Cameroonian medicinal plants: pharmacology and derived natural products. Front. Pharmacol. 123: 1-19.
 
Lenta BN, Vonthron-Sénécheau C, Fongang SR, Tantangmo F, Ngouela S, Kaiser M, Tsamo E, Antone R, Weniger B (2007). In vitro antiprotozoal activities and cytotoxicity of some selected Cameroonian medicinal plants. J. Ethnopharmacol. 111(1):8-12.
Crossref
 
Mehjabeen MA, Noor J, Zia-ul-haq M, Mehboob SA, Asma W, Saeedul-H (2011). Antimicrobial screening of some plants of medicinal importance. Pak. J. Bot. 43(3):1773-1775.
 
Muna MB, Fauzia R El-G (2012). Antibacterial activity of medicinal aqueous plant extracts against Mycobacterium tuberculosis. Mal. J. Microbiol. 8(3):203-206.
 
Njunda AL, Nsagha DS, Assob JCN, Palle JN, Kamga, HLF, Nde PF, Ntube MNC, Weledji PE (2011). Genital mycoplasmas in women attending the Yaoundé University Teaching Hospital in Cameroon. J. Pub. Health Afr. 2:e16
 
Njunda AL, Assob JCN, Nsagha DS, Kamga HLF, Awafong MP, Weledji EP (2012). Epidemiological, clinical features and susceptibility pattern of shigellosis in the Buea Health District, Cameroon. BMC Res. 5:54.
Crossref
 
Nkomo M, Kambizi (2009). Antimicrobial activity of Gunnera perpensa and Heteromorpha arborescens var. abyssinica. J. Med. Plants Res. 3(12):1051-1055.
 
Nsagha DS, Elat, JBN, Ndong PAB, Tata PN, Tayong MN, Pokem F, Wankah CC (2012). Feasibility of home management using ACT for childhood malaria episodes in an urban setting. Drug Healthc. Patient Saf. 4:118.
 
Nsagha DS, Njunda AL, Kamga HLF, Assob JCN, Shey CW, Nsagha SM, Njamnshi AL (2011). Knowledge and practices relating to malaria in Ndu community of Cameroon: signs and symptoms, causes and prevention. J. Public Health Epidemiol. 3(6):294-300.
 
Okokon JE, Nwafor PA (2009). Antiplasmodial activity of root extract and fractions of Croton zambesicus. J. Ethnopharmacol. 121:74-78.
Crossref
 
Olajuyigbe OO, Afolayan AJ (2012). In vitro pharmacological activity of the crude acetone extract of Erythrina caffra Thunb: antibacterial and antifungal assessment. J. Med. Plants Res. 6(9):1713-1720.
Crossref
 
Omoregie ES, Sisodia BS (2012). In vitro antiplasmodial activity and cytotoxicity of leaf extracts of Jatropha tanjorensis. Bayero J. Pure Appl. Sci. 5(1):90–97.
 
Ouattara Y, Sanon S, Traoré Y, Mahiou V, Azas N, Sawadogo L (2006). Antimalarial activity of Swartzia madagascariensis Desv. (Leguminosae), Combretum glutinosum Guill. & Perr. (Combretaceae) and Tinospora bakis miers. (Menispermaceae), Burkina Faso medicinal plants. Afr. J. Trad. CAM. 3 (1):75-81.
 
Owuor B, Kisangau DP (2006). Kenyan medicinal plants used as antivenin: a comparison of plant usage. J. Ethnobiol. Ethnomed 2:7.
Crossref
 
Runyoro DKB, Ngassapa OD, Matee MIN, Joseph CC, Moshi MJ (2006). Medicinal plants used by Tanzanian traditional healers in the management of Candida infections. J. Ethnopharmacol. 106(2):158-165.
Crossref
 
Sawangjaroen N, Sawangjaroen K (2005). "The effect of extracts from anti-diarrheic Thai medicinal plants on the in vitro growth of the intestinal protozoa parasite Blastocytis hominis." J. Ethnopharmacol. 98(1-2):67-72.
Crossref
 
Saxena S, Pant N, Jain DC, Bhakuni RS (2003). Antimalarial agents from plant sources. Curr. Sci. 85:1314-1329.
 
Sendagire H, Kyabayinze D, Swedberg G, Kironde F (2005). Plasmodium falciparum: Higher incidence of molecular resistance markers for sulfadoxine than for pyrimethamine in Kasangati, Uganda. Trop. Med. Int. Health 10:537-543.
Crossref
 
Sha'a KK, Oguche S, Watila IM, Ikpa TF (2011). In vitro antimalarial activity of the extracts of Vernonia amygdalina commonly used in traditional medicine in Nigeria Sci. World J. 6(2): 5-9.
 
Sibanda T, Okoh O (2007). The challenges of overcoming antibiotic resistance: Plant extracts as potential sources of antimicrobial and resistance modifying agents. Afr. J. Biotechnol. 6(25):2886-96.
 
Subeki HM, Tabahashi K, Nabeta K, Ya-masaki M, Maede Y, Katakura K (2007). Screening of Indonesian medicinal plant extracts for antibabesial activity and isolation of new quassinoids from Brucea javanica. J. Nat. Prod. 70(10):1654-1657.
Crossref
 
Titanji VPK, Zofou D, Ngemenya MN (2008). The Antimalarial Potential Of Medicinal Plants Used For The Treatment Of Malaria In Cameroonian Folk Medicine. Afr. J. Trad. CAM 5(3):302-321.
 
Wright CW, Anderson MM, Allen D, Phillipson JD, Kirby GC, Warhurst DC, Chang HR (1993). Quassinoid exhibit greater selecwtivity against Plasmodium falciparum than against Entamoeba histolytica, Giardia intestinalis or Toxoplasma gondii in vitro." J. Eukaryot. Microbiol. 40(3):244- 246.
Crossref
 
Wright CW, O'Neill MJ, Phillipson JD, Warhurst DC (1988). Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica Fruits, Simaruba amara, Stem, and a number of quassinoids. Antimicrob. Agents Chemother. 32(11):1725-1729.
Crossref
 
Zofou D, Tene M, Ngemenya MN, Tane P, Titanji VPK (2011). In vitro Antiplasmodial Activity and Cytotoxicity of Extracts of Selected Medicinal Plants Used by Traditional Healers of Western Cameroon. Malar. Res. Treat. 42:1-6.
Crossref