Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 224

Full Length Research Paper

Antidiabetic potential of liquid-liquid partition fractions of ethanolic seed extract of Corchorus olitorious

Maxwell Osaronowen Egua
  • Maxwell Osaronowen Egua
  • Department of Pharmacology, Usmanu Danfodio University, Sokoto, Nigeria.
  • Google Scholar
Emmanuel Udo Etuk
  • Emmanuel Udo Etuk
  • Department of Pharmacology, Usmanu Danfodio University, Sokoto, Nigeria.
  • Google Scholar
Shaibu Oricha Bello
  • Shaibu Oricha Bello
  • Department of Pharmacology, Usmanu Danfodio University, Sokoto, Nigeria.
  • Google Scholar
Sanusi Wara Hassan
  • Sanusi Wara Hassan
  • Department of Biochemistry, Usmanu Danfodio University, Sokoto, Nigeria.
  • Google Scholar


  •  Accepted: 03 December 2013
  •  Published: 31 January 2014

References

 
Abo KA, Fred-Jaiyesimi AA, Jaiyesimi AEA (2008). Ethnobotannical studies of medicinal plants used in the management of diabetes in southwestern Nigeria. J. Ethno Pharmacol. 11567-11571. Available online at www.Sciencedirect.com.
 
Adegoke AA, Adebayo-Tayo BC (2009). Phytochemical composition and antimicrobial effects of Corchorous olitorius leaf extracts on four bacterial isolates. J. Med. Plants Res. 3(3):155-159
 
Adeneye AA, Adeyemi OO (2009). Hypoglycaemic effects of the aqueous seed extract of Hunteria umbellata in normoglycaemic and glucose and nicotine-induced hyperglycaemic rats. March-April. Int. J. Appl. Res. Nat. Prod. Vol. 2(1):9-18
 
Ahad HA, Padmaja BS, Yesupadam P, Guruprakash P, Sravanthi M, Ramyasree P (2011). Phytochemical and Hypoglycaemic Evaluation of Alangium Salvifolium Root Extract. J. Sci. Res. 3(2):393-402.
 
Atangwho IJ, Ebong PE, Eyong EU, Williams IO, Eteng MU, Egbung GE. Comparative chemical composition of leaves of some antidiabetic medicinal plants: Azadirachta I, Vernonia A (2009). Gongronema latifolium. 15 September. Afr. J. Biotechnol. 8(18):4685-4689.
 
Cunha WR, Arantes GM, Ferreira DS, Lucarini R, Silva MLA, Furtado NAJC, da Silva Filho AA, Crotti AEM, Araujo ARB (2008). Hypoglycemic effect of Leandra lacunose in normal and alloxan induced diabetic rats. FITOTERAPIA.
http://dx.doi.org/10.1016/j.fitote.2008.04.002
PMid:18538949
 
Day C, Cartwright T, Provost J, Bailey CJ (1990). Hypoglycaemic effect of Momordica charantia extracts. Planta Med. 56:426-429.
http://dx.doi.org/10.1055/s-2006-961003
PMid:2077547
 
Diniz SF, Amorim FPLG, Cavalcante-Neto FF, Bocca QL, Batista QC, Simm GEPM, Silva TA (2008). Alloxan-induced diabetes delays repair in a rat model of closed tibial fracture. Braz. J. Med. Bio. Res. Online Ahead of print. ISSN 0100-879X.
 
Dwividendra KN, Pratap S, Rakesh C, Bhaumic G, Narendra K, Rakesh KD (2013). Clinical evaluation of anti-hyperglycemic activity of Boerhaavia diffusa and Ocimum sanctum extracts in streptozocin induced T2DM rat models. Int. J. Pharm. Biomed Sci. 4(1):30-34 ISSN No: 0976-5263.
 
Etuk EU (2010). Animals Models for studying diabetes mellitus. Agric. Biol. J. North Am. ISSN Print; 2151-7517, ISSN Online; 2151-7525.
 
Etuk EU (2006). A review of medicinal plant with hypotensive or anti hypertensive effect. J. Med. Sci. 6(6):894-900.
http://dx.doi.org/10.3923/jms.2006.894.900
 
Fatemeh F, Sanaz H, Mohamad KK, Arash K (2013). Hypoglycemic Activity of Fumaria parviflora in Streptozotocin-Induced Diabetic Rats. Adv Pharm. Bull. 3(1):207-210.
 
Gandhi AP, Joshi KC, Jha K, Parihar VS, Srivastav DC, Raghunadh P, Kawalkar J, Jain SK, Tripathi RN (2003). Studies on alternative solvents for the extraction of oil-I soybean. Int. J. Food Sci. Technol. 38(3):369-375.
http://dx.doi.org/10.1046/j.1365-2621.2003.00683.x
 
George F, Zohar K, Harinder PSM, Klaus B (2002). The biological action of saponins in animal systems: a review. Brit. J. Nutr. 88:587–605.
http://dx.doi.org/10.1079/BJN2002725
PMid:12493081
 
Gill GV, Mbanya JC, Ramaiya KL, Tesfaye S (2009). A sub-Saharan African perspective of diabetes. Diabetologia 52:8-16.
http://dx.doi.org/10.1007/s00125-008-1167-9
PMid:18846363
 
Gowthamarajan K, Sachin KS (2010). Dissolution Testing for Poorly Soluble Drugs: A Continuing Perspective. AUGUST. Dissolution Technologies Pp. 24-32.
 
Holman RR (2013). Type 2 diabetes mellitus in 2012: Optimal management of type 2 diabetes mellitus remains elusive. Nat. Rev. Endocrinol. 9(2):67-68.
http://dx.doi.org/10.1038/nrendo.2012.243
PMid:23296166
 
Huyen VTT, Phan DV, Thang P, Hoa NK, Östenson CG (2013). Clinical Study Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type2 Diabetic Patients. J. Nutr. Metab. 2013:p. 7.
http://dx.doi.org/10.1155/2013/765383
PMid:23431428 PMCid:PMC3572697
 
Kaku N, Hideyuki K, Naoki A, Tozo N, Tatsumasa ML (2004). Flavonoids Suppress Abdominal Fat Accumulation and Increase in Blood Glucose Level in Obese Diabetic KK-Ay Mice. Biol. Pharm. Bull. 27(11):1775-1778.
http://dx.doi.org/10.1248/bpb.27.1775
 
Karl-Heinz D, Robin H, David M, Rudolf P, Yvon R, David S, Jean-Marc V, Cor van de Vorstenbosch (2001). A Good Practice Guide to the Administration of Substances and Removal of Blood, Including Routes and Volumes. J. Appl. Toxicol. 21:15-23.
http://dx.doi.org/10.1002/jat.727
PMid:11180276
 
Leila Z, Eliandra de Sousa, Luisa HC, Anildo C Junior, Moacir GP, Bruno S, Fatima R, Mena BS (2007). Effect of crude extract and fractions from Vitex megapotamica leaves on hyperglycemia in alloxan-diabetic rats. J. Ethnopharmacol. 109:151-155.
http://dx.doi.org/10.1016/j.jep.2006.07.019
PMid:16930892
 
Mohammed A, Adelaiye AB, Abubakar MS, Abdurahman EM (2007). Effects of aqueous extract of Ganoderma lucidum on blood glucose levels of normoglycemic and Alloxan-induced diabetic Wistar rats. J. Med. Plant Res. 1(2):34-37.
 
Nwanjo HU (2007). Studies on the effect of Aqueous extract of Phyllanthus Niruri Leaf on Plasma Glucose Level And some Hepatospecific Markers in Diabetic Zistar Rats. I. J. Lab. Med. Vol. 2(2).
 
Ocho-Anin A, Brou LKD, Kouakou TH, Kouadio YJ, Gnakri D (2010). Screening for antidiabetic activity and phytochemical constituents of common bean (Phaseolus vulgaris L.). 4 September. J. Med. Plants Res. Vol. 4(17):1757-1761,
 
Odebiyi OO, Sofowora EA (1979). Phytochemical screening of Nigerian Medicinal plants 2nd OAU/STRC Inter-African Symposium on Traditional Pharmaco Poeia and African Medicinal Plants (Lagos). 115: 216-220.
 
Ogbonnia SO, Odimegwu JI, Enwuru VN (2008). Evaluation of hypoglycaemic and hypolipidaemic effects of aqueous ethanolic extracts of Treculia africana Decne and Bryophyllum pinnatum Lam. and their mixture on streptozotocin (STZ)-induced diabetic rats. 4 August. Afr. J. Biotechnol. 7(15):2535-2539.
 
Rucha P, Ashish P, Arti J (2010). Antidiabetic effect of Ficus religiosa extract in streptozotocin-induced diabetic rats. J. Ethnopharmacol. 01/2010: 2.32.
 
Sarah W, Gojka R, Anders G, Richard S, Hilary K (2004). Global Prevalence of Diabetes Estimates for the year 2000 and projections for 2030. Diabetes Care 27(5).
 
Taoying Z, Denghong L, Xingyuan L, Yunbo L (2009). Hypoglycemic and hypolipidemic effects of flavonoids from lotus (Nelumbo nuficera Gaertn) leaf in diabetic mice. April. J. Med. Plants Res. 3(4):290-293.
 
Viana GS, Medeiros AC, Lacerda AM, Leal LK, Vale TG, Matos FJ (2004). Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides. BMC Pharmacol. 8:4-9.