Journal of
Parasitology and Vector Biology

  • Abbreviation: J. Parasitol. Vector Biol.
  • Language: English
  • ISSN: 2141-2510
  • DOI: 10.5897/JPVB
  • Start Year: 2009
  • Published Articles: 208

Full Length Research Paper

Influence of infective stage (L3) dose on the outcome of microfilaremia, peripheral white blood cells and humoral immune response in Loa loa experimentally infected Mandrillus sphinx

J. P. Akue
  • J. P. Akue
  • Departement of Medical Parasitology, Centre de Recherches Médicales de Franceville, Gabon.
  • Google Scholar
P. Makouloutou
  • P. Makouloutou
  • Departement of Medical Parasitology, Centre de Recherches Médicales de Franceville, Gabon.
  • Google Scholar
R. M. Moutsimbi
  • R. M. Moutsimbi
  • Departement of Medical Parasitology, Centre de Recherches Médicales de Franceville, Gabon.
  • Google Scholar
H. Moukana
  • H. Moukana
  • Departement of Medical Parasitology, Centre de Recherches Médicales de Franceville, Gabon.
  • Google Scholar
E. Leroy
  • E. Leroy
  • Departement of Medical Parasitology, Centre de Recherches Médicales de Franceville, Gabon.
  • Google Scholar


  •  Received: 01 January 2016
  •  Accepted: 08 April 2016
  •  Published: 30 April 2016

References

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Antonori S, Schifanella L, Million M, Galimberti L, Ferraris L, Mandia L, Trabucchi G, Cacioppo V, Monaco G, Tosoni A, Brouqui P, Gismondo MR, Giuliani G, Corbellino M (2012). Imported Loa loafilariasis: Three cases and a review of cases reported in non-endemic countries in the past 25 years. Int. J. Infect. Dis.16:e649-e662.
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Babayan S, Attout T, Specht S, Hoeurauf A, Renia L, Korenaga M, Bain O, Martin C (2005). Increased early local immune responses and altered worm development in high dose infections of mice susceptible to the filarial Litomosoides sigmondontis. Med. Microbiol. Immunol. 94:151-162.
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Dennis VA, Lowrie RC Jr, Osae-Addo G, Blanchard JL (1993). Microfilarial densities, Hematologic Changes, and Serum Antibody levels in Loa loa-Infected Rhesus Monkeys (Macacamulatta). Am. J. Trop. Med. Hyg. 49:763-771.

 
 

Dupont A, Zue-N'dong J, Pinder M (1988). Common occurrence of amicrofilaraemic Loa loafilariasis within the endemic region. T. R. Soc. Trop. Med. Hyg. 82:730.
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Gardon J, Kamgno J, Fobi G, Essiené A, Ntep M, Gaxotte P, Boussinesq M, Kollo B (1999). Depistage, identification et prise en charge des effets secondaires graves imputables à la loase et au traitement par ivermectine au cours des campagnes de lutte contre l'onchocercose. Bull. Liaison Documentation de l'OCEAC 32:137-52.

 
 

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Leroy E, Baize S, Wahl G, Egwang TG, Georges AJ (1997). Experimental infection of a nonhuman primate with Loa loa induces transient strong immune activation followed by peripheral unresponsiveness of Helper T cells. Infect. Immunol. 65:1876-1882.

 
 

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Nutman B, Thomas V, Kumaraswami V, Ottesen EA (1987). Parasite-specific Anergy in Human Filariasis.Insights after analysis of parasite antigen-driven lymphokine production. J. Clin. Investig. 79:1516-1523.
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Pinder M, Everaere S, Roelants GE (1994). Loa loa: Immunologial responses during experimental infections in Mandrills (Mandrillus sphinx). Exp. Parasitol. 79:126-136.
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Sasisekhar B, Aparna M, Augustin DJ, Kaliraj P, Kar SK, Nutman TB, Narayanan RB (2005). Diminished monocyte function in microfilaremic patients with lymphatic filariasis and its relationship to altered lymphoproliferative responses. Infect. Immunol. 73:3385-3393.
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Towbin HZ, Staehelin T, Gordon J (1979). Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc. Natl. Acad. Sci. USA. 76:4350-4354.
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Van Hoegaerden M, Ivanoff B (1986). A rapid, simple method for isolation of viable microfilariae. Am. J. Trop. Med. Hyg. 35:148-151.

 
 

Wahl G, Moukagni R, Touré F, Georges AJ (1995). Large scale collection of viable larvae of loa loa. Trop. Med. Parasitol. 46:203-204.