Journal of
Veterinary Medicine and Animal Health

  • Abbreviation: J. Vet. Med. Anim. Health
  • Language: English
  • ISSN: 2141-2529
  • DOI: 10.5897/JVMAH
  • Start Year: 2009
  • Published Articles: 350

Full Length Research Paper

Comparison of serum and salivary cortisol in restrained ewe lambs after (Adrenocorticotropic Hormone) ACTH administration

D. T. Yates
  • D. T. Yates
  • Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003, USA.
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L. J. Yates
  • L. J. Yates
  • Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003, USA.
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R. A. Halalsheh
  • R. A. Halalsheh
  • Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003, USA.
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R. L. Wesley
  • R. L. Wesley
  • Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003, USA.
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D. M. Hallford
  • D. M. Hallford
  • Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003, USA.
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T. T. Ross
  • T. T. Ross
  • Department of Animal and Range Sciences, New Mexico State University, Las Cruces, NM 88003, USA.
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  • Article Number - AFD69F21456
  • Vol.2(4), pp. 59-61, November 2010
  •  Accepted: 25 March 2010
  •  Published: 30 November 2010

Abstract

The objective of the current study was to compare cortisol concentrations in serum and salivary samples taken concurrently from halter-restrained lambs administered ACTH (100 IU, i.v.) or saline. Although cortisol appeared elevated in all animals, it tended to increase after ACTH administration in both serum (p = 0.085) and saliva (p = 0.078). Additionally, correlation (r = 0.66; p < 0.001) and regression (R2 = 0.44; p < 0.001) analysis revealed a relationship between cortisol in serum and saliva. Findings indicate that salivary cortisol is indicative of serum cortisol and may provide a viable non-invasive alternative for cortisol quantification.

 

Key words: ACTH challenge, saliva collection, salivary cortisol.