June 2010

Formulation and evaluation of paracetamol tablets manufactured using the dried fruit of Phoenix dactylifera Linn as an excipient

  Dried and milled date palm fruit was evaluated for its binding properties in comparison with acacia and tragacanth. Characterization of the granules in addition to quality control tests that included uniformity of weight, hardness, friability, disintegration and dissolution were undertaken. The granules manufactured using the binders had good flow properties and compressibility. As the concentration of the...

Author(s): N. C. Ngwuluka, B. A. Idiakhoa, E. I. Nep, I. Ogaji and I. S. Okafor

June 2010

Evaluation of okro gum as a binder in the formulation of thiamine hydrochloride granules and tablets

  The aim of this study is to examine the suitability of okro gum as a binder for pharmaceutical tablet formulations. A comparative evaluation of Abelmoschus esculentus (okro) gum as a binder in the formulation of thiamine hydrochloride granules and tablets was performed. Gelatin, acacia and polyvinylpyrrolidone (PVP), were employed as standard binders for comparison. The properties of granules and...

Author(s): G. C. Onunkwo