Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2753


Hydrogen therapy may be a novel, safe and effective treatment for infertility patients with varicocele

Jun Chen1, Mingchao Li2, Bin Zhang1*, Hengjun Xiao3, Tao Qi1, Xuejun Sun4 and Xiao Chen4
1Department of Infertility and Sexual Medicine, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China. 2Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China. 3Department of Urology, the Third Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510630, China. 4Department of Diving Medicine, Second Military Medical University, Shanghai 200433, PR China.
Email: [email protected]

  •  Accepted: 04 November 2011
  •  Published: 09 December 2011


Hydrogen gas recently was discovered as a novel therapeutic medical agent in many biomedical fields. It has potent antioxidant, anti-inflammatory and anti-apoptotic protective effects on cells and organs. Increasing evidence showed that reactive oxygen species (ROS) play an important role in spermatogenesis dysfunction in patients with varicocele. Varicocelectomy and antioxidant treatment can improve the quality of sperm by reducing the production of ROS. Our hypothesis is that hydrogen therapy may be a novel, safe and effective treatment for male infertility with varicocele.


Key words: Hydrogen, therapy, infertility, varicocele.