Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2754

Full Length Research Paper

Effect of the grape seed proanthocyanidin extract on the free radical and energy metabolism indicators during the movement

Ying Shan1*, Xiao-hang Ye1 and Hui Xin2
1Department of Physical Education and Military Training, Zhejiang University of Technology, Hangzhou, Zhejiang Province 310014, China. 2Institute of Physical Education, Minzu University of China, Beijing 100081, China.
Email: [email protected], [email protected]

  •  Accepted: 02 December 2009
  •  Published: 31 January 2010


In order to explore the mechanism of grape seed proanthocyanidin extract (GSPE) against exercise-induced fatigue, the mice movement model was used, and the free radical and energy metabolism indicators during movement were measured. The results show that grape seed proanthocyanidin extract can improve the activity of antioxidant enzymes such as SOD and GSH-Px in the liver in exercised mice, and lower the MDA content, which may produce the effect of anti-oxidation by increasing the activity of antioxidant enzyme in the body; GSPE can keep the blood glucose in exercised mice on a stable level, increase the liver glycogen and muscle glycogen reserves, and prevent the blood glucose content, as well as the liver glycogen and muscle glycogen content, reducing after long time exercise; Meanwhile, GSPE can improve the level of TC, TG and FFA in plasma in exercised - mice, influence the fat metabolism under different conditions and promote the fat utilization. All the results above may be the anti-fatigue mechanism of GSPE.


Key words: Grape seed proanthocyanidin extract, free radicals, energy metabolism.