Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2753

Full Length Research Paper

Predictors for clinical outcome in patients with ectopic pregnancy after conservative treatment

  Yuxia Wang1*, Xingmei Xie1, Xiaolan Shi2, Jianqiang Liu2 and Ming Dai3
    1Department of Obstetrics and Gynecology, First Clinical College, Jinan University, Guangzhou 510630, China. 2Department of Ultrasonography, First Clinical College, Jinan University, Guangzhou 510630, China. 3Department of Obstetrics and Gynecology, Qifu Hospital, Traditional Chinese Medicine University of Guangzhou, Guangzhou 511495, China.  
Email: [email protected]

  •  Accepted: 24 November 2010
  •  Published: 31 December 2010

Abstract

 

 

To investigate the outcome predictors in conservative treatment of ectopic pregnancy, a total of 163 patients in our hospital and 120 patients in a primary hospital were recruited into the present study from December 2008 to November 2009. These patients were all diagnosed of ectopic pregnancy. The clinical value of serum β-HCG and progesterone levels before and during conservative treatment and blood flow signals and features of gestation sacs in ultrasonography on the therapeutic outcomes was retrospectively investigated. Serum β-HCG<2000 IU/ml, P<20 ng/ml and blood flow signals of lower than grade 2 before conservative treatment predicted a high success rate. In addition, on day 7 of conservative treatment, serum β-HCG was decreased by more than 15 to 20% and the grade of blood flow signals markedly decreased in ultrasonography, which predicted a high success rate. The success rate of conservative treatment in our hospital was significantly higher than that in the primary hospital. Serum levels of β-HCG, and P in combination with blood flow signals and features of gestation sacs under transvaginal ultrasonography are outcome predictors in patients with ectopic pregnancy after conservative treatment.

 

Key words: β-HCG, progesterone, transvaginal ultrasonography, ectopic pregnancy.