To investigate the outcome predictors in conservative treatment of ectopic pregnancy, a total of 163 patients in our hospital and 120 patients in a primary hospital were recruited into the present study from December 2008 to November 2009. These patients were all diagnosed of ectopic pregnancy. The clinical value of serum β-HCG and progesterone levels before and during conservative treatment and blood flow signals and features of gestation sacs in ultrasonography on the therapeutic outcomes was retrospectively investigated. Serum β-HCG<2000 IU/ml, P<20 ng/ml and blood flow signals of lower than grade 2 before conservative treatment predicted a high success rate. In addition, on day 7 of conservative treatment, serum β-HCG was decreased by more than 15 to 20% and the grade of blood flow signals markedly decreased in ultrasonography, which predicted a high success rate. The success rate of conservative treatment in our hospital was significantly higher than that in the primary hospital. Serum levels of β-HCG, and P in combination with blood flow signals and features of gestation sacs under transvaginal ultrasonography are outcome predictors in patients with ectopic pregnancy after conservative treatment.

Key words: β-HCG, progesterone, transvaginal ultrasonography, ectopic pregnancy.