Renoprotective and antioxidant effects of methanol extract and fraction of Oxytenanthera abyssinica leaf (Poaceae) in diabetic nephropathy in rats.

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Diabetic nephropathy is a major life-threatening complication in diabetic individuals. The present study investigated the protective effects and the antioxidant activity of Met-E and Met-F from Oxytenanthera abyssinica leaf. An oral dose of 400 mg/kg of Met-E and Met-F were administered during four weeks to diabetic rats. The diabetic nephropathy was experimentally evidenced by an increase in renal function markers’level...

Author(s):Atchrimi Komi Sagnan