March 2021

Primary and secondary resistance to first-line anti-tuberculosis medications at the Institute Pasteur Bangui, Central African Republic

The emergence and spread of anti-tuberculosis-resistant strains of Mycobacterium tuberculosis presently represents a real challenge to the WHO's End TB by 2035 strategy. Through this study, we wanted to determine the current prevalence of primary and secondary resistance to first-line anti-tuberculosis drugs at the Pasteur Institute in Bangui. Cultures and sensitivity tests were carried out for 6 months (July -...

Author(s): Alain Farra, Boris Jolly, Gilles Ngaya, Herve Gando, Aristide Desire Komamgoya-Nzonzon, and Alexandre Manirakiza