Biotechnology and Molecular Biology Reviews

  • Abbreviation: Biotechnol. Mol. Biol. Rev.
  • Language: English
  • ISSN: 1538-2273
  • DOI: 10.5897/BMBR
  • Start Year: 2006
  • Published Articles: 103

Table of Content: April 2011; 6(3)

April 2011

In silico modeling in conjunction with natural products: Paving the way for rational drug-design

Genome sequencing projects has produced a vast wealth of data describing the protein coding regions of the genome under study. However, only a minority of the protein sequences identified has a clear sequence homology to a known protein. In such cases valuable three-dimensional models of the protein coding sequence can be constructed by homology modeling methods. Threading methods uses specialized schemes to relate...

Author(s): Shailza Singh and D. K. Sharma

April 2011

Toxigenic Escherichia coli and Vibrio cholerae: Classification, pathogenesis and virulence determinants

Escherichia coli and Vibrio cholerae are pathogenic bacteria commonly found in various contaminated sources and pose a major health risk, causing a range of human enteric infections and pandemics, especially among infants in Africa. Virulence and pathogenesis of these organisms is specifically based on the expression of certain virulence determinants, distinctive mucosal interactions as well as the...

Author(s): Ademola O. Olaniran, Kovashnee Naicker and Balakrishna Pillay