August 2007
Plant protease inhibitors: a defense strategy in plants
Proteases, though essentially indispensable to the maintenance and survival of their host organisms, can be potentially damaging when overexpressed or present in higher concentrations, and their activities need to be correctly regulated. An important means of regulation involves modulation of their activities through interaction with substances, mostly proteins, called protease inhibitors. Some insects and many of the...
August 2007
Analysis and manipulation of the genome dynamic structure
After the genomic era, during which DNA sequencing revealed genes and the post-genomic era, in which their functional analysis was implemented, the notion of a dynamic genome has become convincing. Indeed, since the early days of DNA transposition, new evidence has accumulated indicating a high level of intrinsic structural plasticity characterizing the genome. An ensemble of gross chromosomal rearrangements...
August 2007
Cationic lipids used in non-viral gene delivery systems
To perform gene transfer two types of vectors are available, (i) viral vectors (ii) nonviral vectors. Among the vectors, nonviral vectors have proved less toxic and safe compare to viral vectors through clinical trials. No single vector is proved suitable for every gene transfection experiment. Cationic lipids are experimentally established as non-viral vector with higher transfection efficiency....
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