December 2007
Current trends in molecular epidemiology studies of Mycobacterium tuberculosis
Mycobacterium tuberculosis is one of the most harmful human pathogens worldwide, and there are mass efforts for controlling this pathogen. One of the powerful tools to find out and control this pathogen is molecular epidemiology techniques. Currently, wide ranges of techniques are available to type mycobacterium tuberculosis, and choosing the correct technique as a portable and standard method is...
December 2007
Genetic aspects of ameloblastoma: a brief review
Ameloblastomas are defined as aggressive neoplasms arising from the odontogenic epithelium which exhibit a locally invasive behavior with a high rate of recurrence. If left untreated, they often lead to extensive tissue destruction and deformity. Due to the fact that these tumors emerge from remnants of normal odontogenic apparatus, which is strictly regulated through several genes, studies have...
December 2007
Computational aspects of thematics: application to protein tyrosine phosphatase role in diabetes mellitus
Computation plays an important role in functional genomics and proteomics. Theoretical Microscopic Titration Curves (Thematics) are being employed to predict active binding sites of enzymes. The principal reasons are that the pace of discovery of new proteins is increasing, outpacing the ability to characterize them in conventional biochemical and structural techniques; in addition, advances...
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