October 2010

Engineered pathogenesis related and antimicrobial proteins weaponry against Phytopthora infestans in potato plant: A review

Phytopthora infestans (Mont.) de Bary, causal organism of late blight disease is referred to as the most destructive specific pathogen of potato (Solanum tuberosum L.). Casualties usually go beyond mere plant destruction, due to its flaring ability to also demolish scientific concerted efforts in establishing novel combat techniques. With high capacity to overcome control measures, it stands at par, and...

Author(s): Bengyella Louis and Pranab Roy

October 2010

Probing yeast for insights into neurodegenerative disease: ORFeome-wide screens for genetic modifiers of α-synuclein cytotoxicity

Several of the most devastating neurodegenerative disorders, including Parkinson’s disease and dementia with Lewy bodies, belong to the synucleinopathy class of common neural disorders. A synucleinopathy is characterized by brain tissue plaques formed by the aggregation of misfolded protein―mainly misfolded α-synuclein. α-Synuclein has been extensively studied as the primary protein aggregate in...

Author(s): Richard A. Manfready,