Journal of
Bioinformatics and Sequence Analysis

  • Abbreviation: J. Bioinform. Seq. Anal.
  • Language: English
  • ISSN: 2141-2464
  • DOI: 10.5897/JBSA
  • Start Year: 2009
  • Published Articles: 46

Table of Content: February 2013; 5(2)

February 2013

Prediction of MHC Class II binders/non-binders using negative selection algorithm in vaccine designing

  The identification of major histocompatibility complex (MHC) class-II restricted peptides is an important goal in human immunological research leading to peptide based vaccine designing. These MHC class II peptides are predominantly recognized by CD4+ T-helper cells, which when turned on, have profound immune regulatory effects. Thus, prediction of such MHC class-II binding peptide is very helpful towards...

Author(s): S. S. Soam, Feroz Khan, Bharat Bhasker and B. N. Mishra

February 2013

In silico identification of miRNAs and their target prediction from Japanese encephalitis

  MicroRNA is a family of small non-coding RNAs that regulate gene expression in a sequence-specific manner. miRNAs are a class of post-transcriptional regulators. miRNAs are a family of 19 to 25 small nucleotide RNAs. Since miRNAs have been discovered and their role in gene regulation established, it has been theorized that viruses could generate miRNAs as well and that these viral encoded miRNAs could...

Author(s): Vijay Laxmi Saxena and Alka Dwivedi