December 2011

Bind-Predict: An algorithm for identifying zinc finger binding motifs in DNA sequences

Zinc fingers are the most abundant eukaryotic DNA-binding motifs, which recognize DNA triplets with high efficacy and are used to develop chimeric enzymes for genome modification and site specific gene therapy. Considering the importance of zinc finger motifs and their recognition patterns we have developed a web interface with the incorporation of sequence based search algorithm named as Bind-Predict. This algorithm...

Author(s): Jayaraman Muthukumaran, Mannu Jayakanthan, Sanniyasi Chandrasekar and Premendu P. Mathur

December 2011

Nuclear mitochondrial DNA pseudogenes in the genome of the silkworm, Bombyx mori

To understand the types of mitochondrial deoxyribonucleic acid (mtDNA) pseudogenes in the genome of the silkworm Bombyx mori L. (Lepidoptera: Bombycidae) and to determine the origin of the B. mori, the mtDNA of the wild silkworm, Bombyx mandarina Morre was sequenced. Several fragments from the B. mori genome database were obtained with varying degrees of homology toB....

Author(s): Guangli Cao, Renyu Xue, Yuexiong Zhu, Yuhong Wei and Chengliang Gong,