April 2012
The p53 status in patients with common variable immunodeficiency
Common variable immunodeficiency (CVID) comprises a heterogeneous group of primary antibody deficiencies with complex clinical and immunological phenotypes. A high risk for cancer has been described for some types of cancer among patients with CVID. Mutations in p53, a critical tumor suppressor gene, are one of the most common genetic alterations in human cancers, therefore contributes to the complex network of...
April 2012
A review of the types of presentation among positive angiographic acute coronary syndrome patients in Hospital Universiti Sains Malaysia
Atypical presentation of myocardial infarction is recognized as an important manifestation of coronary heart disease associated with unfavorable prognosis. Understanding the spectrum of clinical symptoms and presentations are essential to diagnose and deliver appropriate rapid treatment to patients in the emergency department. Hence, this study was carried out to identify the type of presentation of acute coronary...
April 2012
In vitro and in vivo evaluation of acetylsalicylic acid in Khat (Qat) chewing healthy volunteers
Aspirin is being extensively used in Yemen as analgesic, antipyretic, anti-inflammatory and anti-platelets aggregation for prophylaxis of thrombotic heart diseases. The objective of this study was to evaluate 2 common brands of aspirin present in the market, weight variation, disintegration and dissolution, hardness and drug content and the effect of Khat chewing on their bioavailability. 28 healthy male volunteers (14...
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