March 2013

Coronary artery by pass grafting and lung lobectomy: Functional outcomes at discharge

Mortality and complication rates after on-pump versus off-pump coronary artery bypass grafting (CABG), and open lung lobectomy (OL) versus video-assisted lobectomy (VAL), have previously been reported, but further research regarding functional outcomes is needed. This study compared functional recovery at discharge between patients who underwent on-pump versus off-pump CABG, and OL versus VAL. In patients discharged...

Author(s): Kazuaki Kuwabara, Shinya Matsuda, Kiyohide Fushimi, Koichi B. Ishikawa, Hiromasa Horiguchi and Kenji Fujimori

March 2013

In vitro preventive effects of nitrate tolerance by a polyphenol-enriched extract of Hibiscus sabdariffa

Treatment failure or tolerance, which rapidly leads to a reduced hemodynamic effects and therapeutic efficacy is the major limitation of long-term use of nitrates, including nitroglycerin (NTG) in the treatment of coronary artery disease. These effects are most often associated with oxidative stress. Thus, in this work, we were interested in the prevention of nitrate tolerance by the antioxidant compounds...

Author(s): Mamadou Sarr, Fatou B. Sar, Maboury Diao, Saliou Ngom, Alassane Wele, Lamine Guèye, Fallou Cissé and Annelise Lobstein