April 2011

Imaging modalities in head and neck cancer patients-overview

Accurate staging and timely assessment in head and neck cancer patients is critical for initiating appropriate treatment strategy. Therefore, pre-treatment imaging in diagnosis is of great importance. Computerized tomography, introduced in the early 70s, followed by magnetic resonance imaging, positron emission tomography, refinements in ultrasonography, and advances in nuclear medicine and applications such as sentinel...

Author(s): M. E. Sham and S. Nishat

April 2011

Photochemical internalization: Maximizing the potential of siRNA in cancer therapy through spatially and temporally controlled endolysosomal escape

A major obstacle for cancer therapies is the lack of targeted delivery of therapeutics. To compensate, existing drug treatments rely on high dosages and frequent administrations. This results in adverse effects in the patient due to the drugs failure to discriminate between normal body cells and tumor cells. The discovery of RNAi (RNA interference) has radically opened possibilities to the advancement of cancer...

Author(s): Md Iqbal Touhid, B. S.