December 2011

Evidence of a positive correlation between accelerated oestrogen receptor phosphorylation and breast cancer progression

Estrogen receptor beta (ERβ) is predicted to play an important role in prevention of breast cancer development and metastasis. Phosphorylation of Estrogen receptor alpha (ERα) has been proven to be involved in the progression of breast cancer and it is believed oestrogen receptor beta too phosphorylated at multiple sites within the protein upon ligand binding although the exact function of this...

Author(s): Mohamed Fareez Meerasahib and Amer Hamzah Asseri