June 2011

Genetic polymorphisms of GSTM1 and GSTT1 genes and endometrial cancer in Basrah, South of Iraq

The genes glutathione S- transferase M1 (GSTM1) and GSTT1 involved in phase II metabolism catalyse glutathione – mediated reduction of exogenous and endogenous electrophiles. A case control study was designed to identify association between polymorphisms at GSTM1 and GSTT1 genes and endometrial cancer risk. Genotype frequencies in 50 patient’s women with endometrial cancer...

Author(s): Adnan Issa Al-Badran

June 2011

Down regulation of galectin-3 in primary tumor tissues of breast predict axillary lymph node metastasis

Identification of axillary lymph node metastasis in breast cancer patients is a challenge in routine pathology practice. Serial sectioning and immunohistochemistry is labor intensive and cannot be followed even for sentinel node examination. So identification of a biomarker predicting axillary lymph node metastasis in primary tumor tissue is of great interest. Galectins are a family of low molecular weight...

Author(s): K. Sujathan, Thara Somanathan, Nimi G. K., Preethi Sara George, Elizabeth K. Abraham and P. Remani