September 2013
Hepatoprotective and anti-diabetic effect of combined extracts of Moringa oleifera and Vernonia amygdalina in streptozotocin-induced diabetic albino Wistar rats
This study was carried out to investigate the hepato-protective properties of combined extracts of Moringa oleifera (MO) and Vernonia amygdalina (VA) in streptozotocin (STZ) induced diabetic albino Wistar rats. The study design involved 42 rats weighing 120 to 180 g which were divided into 7 groups of 6 rats each. Groups 1 and 2 representing normal and diabetic control (NC and DC) received 0.5 ml of...
September 2013
Comparison between the clinical efficacy of linagliptin and sitagliptin
After the introduction of dipeptidylpeptidase-4 (DPP-4) inhibitors into the treatment for diabetes, these drugs have been widely used because of their capability and safety. Therefore, the clinical efficacy of linagliptin to sitagliptin was compared. Patients with type 2 diabetes, in whom pharmacological treatment was recently started, were randomly assigned to two separate groups, namely sitagliptin (50 mg/day) group...
