January 2011
Evaluation of glycemic control, gastric juice nitric oxide and oxidative stress in diabetic patients infected by Helicobacter pylori
Recently, diabetes mellitus has been known as one of the main cause of upper gastrointestinal symptoms. It has also been suggested that delayed gastric emptying may lead to bacterial overgrowth in the upper gastrointestinal tract. Since high prevalence of Helicobacter pylori (H. pylori) in diabetic patients has been reported. The aim of this study was to evaluate the relationship between dyspepsia, the level...
January 2011
hTERT gene inhibition studies in cancer cells by using polysaccharide lentina
Lentinan a polysaccharide from medicinal mushroom that is Lentinus has been known to have anticancer properties. Telomerase activity is not observed in normal healthy cells, where as in cancerous cells telomerase expression is high. Telomerase represents a promising cancer therapeutic target. We investigated the inhibitory effect of lentinan on telomerase reverse transcriptase gene (hTERT) which is essential for...
January 2011
Evidence of association of a common variant of the endothelial nitric oxide synthase gene (Glu298 →Asp polymorphism) to coronary artery disease in South Indian population
Genetic variants of endothelial nitric oxide synthase (eNOS) could influence individual susceptibility to coronary artery disease (CAD) with or without association with demographic factors. This study was designed to assess the Glu298 /Asp variant of the eNOS gene in 79 patients with CAD as compared to equal number (79) of controls. The genotype frequencies for eNOS gene polymorphism were determined by PCR and RFLP, and...
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